Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028572 | 0.85 | CYP19A1 (0.35) | CYP19A1BRD4EP300CREBBPSIGMAR1 | |
| SCHEMBL13871619 | 0.81 | CNR2 (0.47) | — | |
| SCHEMBL14538579 | 0.76 | CYP19A1 (0.36) | CYP19A1BRD4SIGMAR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13871505 | 0.67 | CNR2 (0.52) | — | |
| SCHEMBL10216961 | 0.67 | CNR2 (0.52) | — | |
| SCHEMBL13871389 | 0.65 | ALDH1A1 (0.58) | BRD4SIGMAR1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL300508 | 0.64 | CNR2 (0.46) | — | |
| SCHEMBL182893 | 0.64 | FABP4 (0.49) | SIGMAR1KMT2AMEN1LMNATSHR | |
| SCHEMBL300478 | 0.64 | FABP4 (0.50) | SIGMAR1KMT2AMEN1TSHRHPGD | |
| SCHEMBL10216949 | 0.64 | MEN1 (0.48) | SIGMAR1SMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |