Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176602 | 0.83 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL14267672 | 0.82 | CNR1 (0.38) | SMN1; SMN2ALDH1A1CNR2CNR1RIPK1 | |
| SCHEMBL13871547 | 0.80 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL3467155 | 0.78 | MEN1 (0.42) | SMN1; SMN2ALDH1A1CNR2CNR1CCNA2 | |
| SCHEMBL176699 | 0.77 | ALDH1A1 (0.46) | ALDH1A1CNR2CNR1SMYD3 | |
| SCHEMBL177139 | 0.76 | KMT2A (0.54) | SMN1; SMN2ALDH1A1CNR2CNR1CCNA2 | |
| SCHEMBL176709 | 0.76 | CNR1 (0.43) | SMN1; SMN2ALDH1A1CNR2CNR1SIGMAR1 | |
| SCHEMBL13871545 | 0.76 | CNR1 (0.43) | SMN1; SMN2ALDH1A1CNR2CNR1RIPK1 | |
| SCHEMBL13889389 | 0.76 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1CNR2CNR1CRHBP | |
| SCHEMBL14028632 | 0.76 | CYP19A1 (0.37) | CYP19A1SMN1; SMN2ALDH1A1BRD4CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123578-A1 | Hexahydro-cycloheptapyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123578-A1 | Hexahydro-cycloheptapyrazole cannabinoid modulators | CNR2, CNR1, FAAH | CYP19A1 1593/4885SMN1; SMN2 3095/4885ALDH1A1 1422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.