Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028930 | 1.00 | ALDH1A1 (0.50) | ALDH1A1PREPTSHRMEN1KMT2A | |
| SCHEMBL14028937 | 1.00 | ALDH1A1 (0.50) | ALDH1A1PREPTSHRMEN1KMT2A | |
| SCHEMBL9191610 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PREPTSHRMEN1KMT2A | |
| SCHEMBL9194320 | 0.83 | ALDH1A1 (0.46) | ALDH1A1PREPTSHRMEN1KMT2A | |
| SCHEMBL27449506 | 0.78 | ALDH1A1 (0.45) | ALDH1A1PREPTSHRMEN1KMT2A | |
| SCHEMBL9187736 | 0.78 | ALDH1A1 (0.42) | ALDH1A1PREPTSHRMEN1KMT2A | |
| SCHEMBL9187721 | 0.78 | ALDH1A1 (0.42) | ALDH1A1PREPTSHRMEN1KMT2A | |
| SCHEMBL9187730 | 0.78 | ALDH1A1 (0.42) | ALDH1A1PREPTSHRMEN1KMT2A | |
| SCHEMBL9189776 | 0.78 | ALDH1A1 (0.47) | ALDH1A1PREPTSHRGRM2KCNA5 | |
| SCHEMBL4317709 | 0.77 | ALDH1A1 (0.44) | ALDH1A1PREPTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442793-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-28 | — | — | US | disclosed |
| US-20070173542-A1 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173542-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | ALDH1A1 4302/4885PREP 6/4885TSHR 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.