Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962874 | 0.79 | EPHX2 (0.46) | EPHX2TYK2NR1H4PPARGGRIN1 | |
| SCHEMBL3513834 | 0.71 | TYK2 (0.63) | TYK2 | |
| SCHEMBL4994139 | 0.71 | ALDH1A1 (0.59) | TYK2APEX1 | |
| SCHEMBL16742649 | 0.69 | TDP1 (0.59) | EPHX2NR1H4GRIN1GRIN2B | |
| SCHEMBL13034388 | 0.68 | HPGD (0.47) | EPHX2CA1CA2GRIN1KCNH2 | |
| SCHEMBL12764248 | 0.67 | CA1 (0.47) | EPHX2CA1CA2APEX1L3MBTL1 | |
| SCHEMBL5342654 | 0.66 | KEAP1 (0.53) | CA1CA2 | |
| Hydrochloric Acid SCHEMBL4577309 | 0.66 | KEAP1 (0.53) | CA1CA2 | |
| SCHEMBL1016072 | 0.66 | ACLY (0.58) | EPHX2NR1H4PPARG | |
| SCHEMBL12985489 | 0.65 | HPGD (0.45) | EPHX2CA1CA2NR1H4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452905-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2008-11-18 | — | — | US | disclosed |