Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 1.00 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.58 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133904 | 1.00 | CYP11B2 (1.00) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| SCHEMBL23873927 | 1.00 | CYP11B2 (1.00) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| SCHEMBL6095783 | 0.98 | CYP11B2 (0.96) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| SCHEMBL30434052 | 0.94 | CYP11B2 (0.88) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| SCHEMBL26154135 | 0.94 | CYP11B2 (0.88) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| SCHEMBL29848157 | 0.89 | — | — | |
| SCHEMBL990213 | 0.89 | — | — | |
| Cyanide SCHEMBL28217286 | 0.88 | CYP11B2 (0.79) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| Formic Acid SCHEMBL28324256 | 0.87 | CYP11B2 (0.77) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| Ammonia Solution, Strong SCHEMBL28985148 | 0.87 | CYP11B2 (0.77) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275253-A1 | halogenation with a halogen donor selected from N-bromosuccinimide, N-iodosuccinimide, N-chlorosuccinimide and N-fluorobenzene-sulfonimide, 1,3-dibromo-5,5-dimethyl imidazolidine-2,4-dione in presence of ZrCl4; bromination of tetramethylsilane | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275253-A1 | halogenation with a halogen donor selected from N-bromosuccinimide, N-iodosuccinimide, N-chlorosuccinimide and N-fluorobenzene-sulfonimide, 1,3-dibromo-5,5-dimethyl imidazolidine-2,4-dione in presence of ZrCl4; bromination of tetramethylsilane | HDHD5, ZRANB2, CLIC4 | CYP11B2 4085/4885CHRNB2 2265/4885CHRNA4 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.