Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.96 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.51 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133904 | 0.98 | CYP11B2 (1.00) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| SCHEMBL23873927 | 0.98 | CYP11B2 (1.00) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| SCHEMBL14029295 | 0.98 | CYP11B2 (1.00) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| SCHEMBL30434052 | 0.96 | CYP11B2 (0.88) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| SCHEMBL26154135 | 0.96 | CYP11B2 (0.88) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| SCHEMBL29848157 | 0.91 | — | — | |
| SCHEMBL990213 | 0.91 | — | — | |
| Cyanide SCHEMBL28217286 | 0.90 | CYP11B2 (0.79) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| Formic Acid SCHEMBL28324256 | 0.89 | CYP11B2 (0.77) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 | |
| Ammonia Solution, Strong SCHEMBL28985148 | 0.89 | CYP11B2 (0.77) | CYP11B2CHRNB2CHRNA4CHRNA7CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646542-A | Method using microwave method to synthesize cefpirome sulfate | 上海宁瑞生化技术有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-103539736-B | Method for synthesis of 2,3-cyclopentenopyridine from glycerin as raw material | INST OF INDUSTRY ZHIJIANG COLLEGE OF ZHEJIANG UNIVERSITY OF TECHNOLOGY | 2015-05-13 | — | — | CN | claimed |
| CN-103601738-A | Preparation method of cefpirome hydriodate | HARBIN PHARMACEUTICAL GROUP CO LTD GENERAL PHARMACEUTICAL FACTORY | 2014-02-26 | — | — | CN | claimed |
| CN-103539736-A | Method for synthesis of 2,3-cyclopentenopyridine from glycerin as raw material | IND RES INST ZHIJIANG COLLEGE OF ZHEJIANG UNIV TECHNOLOGY | 2014-01-29 | — | — | CN | claimed |
| CN-102744056-A | Ti-V loaded aluminum-pillared montmorillonite heterogeneous catalyst and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2012-10-24 | — | — | CN | claimed |
| CN-102584856-A | Method for preparing cefpirome sulfate | KAIFENG YUGANG PHARMACEUTICAL CO LTD | 2012-07-18 | — | — | CN | claimed |
| CN-101284840-B | Synthetic method of cefpirome sulfate | XIAOMING GUAN | 2012-07-04 | — | — | CN | claimed |
| CN-102391288-A | Preparation methods of cefpirome intermediate and cefpirome | QILU ANTIBIOTICS PHARMACEUTICAL CO LTD | 2012-03-28 | — | — | CN | claimed |
| CN-101337970-B | Method for synthesizing antibiotic cefpirome sulfate | SUZHOU WANQING PHARMACEUTICAL CO LTD | 2011-02-02 | — | — | CN | claimed |
| CN-101747349-A | Method for synthesizing cefpirome sulfate | SHANDONG XINQUAN MEDICINE INTE | 2010-06-23 | — | — | CN | claimed |
| CN-101456870-A | Novel process for synthesizing cefpirome sulfate | BEIJING HOPE HUGE PHARM SCI CO (CN) | 2009-06-17 | — | — | CN | claimed |
| CN-101337970-A | Synthesis method of antibiotic cefpirome sulfate | SUZHOU WANQING PHARMACEUTICAL (CN) | 2009-01-07 | — | — | CN | claimed |
| CN-101284840-A | Synthetic method of cefpirome sulfate | XIAOMING GUAN (CN) | 2008-10-15 | — | — | CN | claimed |
| CN-1907973-A | Process for preparing 2,3-cyclopentene pyridine | JINAN CHENGHUI SHUANGDA CHEMIC (CN) | 2007-02-07 | — | — | CN | claimed |
| CN-1680329-A | Preparation of pyridine derivative | ZHEJIANG INDUSTRY UNIV (CN) | 2005-10-12 | — | — | CN | claimed |
| CN-115677569-B | Synthesis method of pyridines and substituted benzenes based on reduction coupling reaction of iron-catalyzed aryl halide and alkyl halide | 重庆大学 | 2024-05-28 | — | — | CN | disclosed |
| US-20230271975-A1 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-08-31 | — | — | US | disclosed |
| US-20040229864-A1 | Sulfone derivatives as 5-HT7 receptor ligands | MERCK SHARP & DOHME LTD. (GB) | 2004-11-18 | — | — | US | disclosed |
| CN-1024011-C | Process for producing cephalosporin compound | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-03-16 | — | — | CN | disclosed |
| CN-1050023-A | The method for preparing cephalosporin derivative | BEECHAM GROUP PLC (GB) | 1991-03-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229864-A1 | Sulfone derivatives as 5-HT7 receptor ligands | HTR7, HTR2C, HTR1A | CYP11B2 452/4885CHRNB2 165/4885CHRNA4 208/4885 |
| US-20230271975-A1 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | ALK, ACVR2B, ACVR2A | CYP11B2 1165/4885CHRNB2 3330/4885CHRNA4 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.