Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14033848 | 0.84 | ADORA2A (0.31) | — | |
| SCHEMBL8400149 | 0.82 | IDO1 (0.32) | — | |
| SCHEMBL14033246 | 0.81 | MEN1 (0.37) | CHRM4CTNNB1WNT3A | |
| SCHEMBL9962275 | 0.75 | GABRA1 (0.38) | TSHR | |
| SCHEMBL23232390 | 0.72 | CYP1A2 (0.38) | — | |
| SCHEMBL3704838 | 0.72 | CYP1A2 (0.38) | — | |
| SCHEMBL18500388 | 0.71 | IDO1 (0.37) | — | |
| SCHEMBL14033759 | 0.71 | CTNNB1 (0.43) | TSHRCTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL3697431 | 0.71 | ALDH1A1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL26100881 | 0.71 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7432268-B2 | 17β-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases | SCHERING CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |