Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14033237 | 0.82 | TSHR (0.31) | — | |
| SCHEMBL9962275 | 0.81 | GABRA1 (0.38) | IDO1MPODOT1LADORA2AGPR3 | |
| SCHEMBL8400006 | 0.79 | AHR (0.31) | — | |
| SCHEMBL23232390 | 0.79 | CYP1A2 (0.38) | IDO1MPODOT1LADORA2A | |
| SCHEMBL3704838 | 0.79 | CYP1A2 (0.38) | IDO1MPODOT1LADORA2A | |
| Hydrochloric Acid SCHEMBL3697431 | 0.77 | ALDH1A1 (0.40) | IDO1MPODOT1LADORA2A | |
| SCHEMBL18500388 | 0.77 | IDO1 (0.37) | IDO1MPOADORA2AFFAR4 | |
| SCHEMBL31177508 | 0.76 | MPO (0.32) | MPOADORA2AFFAR4 | |
| SCHEMBL18856202 | 0.76 | MPO (0.32) | IDO1MPOGPR3 | |
| SCHEMBL8951956 | 0.75 | IDO1 (0.32) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759433-B1 | Process for the preparation of 2,2-difluorobenzo[1.3]dioxolcarbaldehydes | BAYER AG (DE) | 1999-06-16 | — | — | EP | claimed |
| US-5637737-A | Process for the preparation of 2,2-difluorobenzo[1.3]dioxolecarbaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | claimed |
| EP-0759433-A1 | Process for the preparation of 2,2-difluorobenzo(1.3) dioxolcarbaldehydes | BAYER AG (DE) | 1997-02-26 | — | — | EP | claimed |
| EP-0537517-B1 | Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates | BAYER AG (DE) | 1997-01-22 | — | — | EP | claimed |
| US-5525739-A | Process for the preparation of 2,2-difluorobenzo[1,3]-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-11 | — | — | US | claimed |
| EP-0537517-A1 | Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | claimed |
| JP-9067366-A | — | — | None | — | — | JP | disclosed |
| JP-5194478-A | — | — | None | — | — | JP | disclosed |
| EP-0759433-B1 | Process for the preparation of 2,2-difluorobenzo[1.3]dioxolcarbaldehydes | BAYER AG (DE) | 1999-06-16 | — | — | EP | disclosed |
| US-5637737-A | Process for the preparation of 2,2-difluorobenzo[1.3]dioxolecarbaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | disclosed |
| US-5637737-A | Process for the preparation of 2,2-difluorobenzo[1.3]dioxolecarbaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 1997-06-10 | — | — | US | disclosed |
| JP-H0967366-A | PRODUCTION OF 2,2-DIFLUOROBENZO(1.3)DIOXOLCARBALDEHYDE COMPOUNDS | BAYER AG | 1997-03-11 | — | — | JP | disclosed |
| EP-0759433-A1 | Process for the preparation of 2,2-difluorobenzo(1.3) dioxolcarbaldehydes | BAYER AG (DE) | 1997-02-26 | — | — | EP | disclosed |
| US-5525739-A | Process for the preparation of 2,2-difluorobenzo[1,3]-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5525739-A | Process for the preparation of 2,2-difluorobenzo[1,3]-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5420308-A | 2,2-difluorobenzo (1,3)-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-30 | — | — | US | disclosed |
| US-5420308-A | 2,2-difluorobenzo (1,3)-dioxole-carbaldehydes and new intermediate products | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-30 | — | — | US | disclosed |
| JP-H05194478-A | PRODUCTION OF 2,2-DIFLUOROBENZO(1,3)-DIOXYOLE-CARBALDEHYDE AND NEW INTERMEDIATE PRODUCT | BAYER AG | 1993-08-03 | — | — | JP | disclosed |
| EP-0537517-A1 | Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0537517-A1 | Method for the preparation of 2,2-difluorobenzo(1,3)dioxolecarbaldehydes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |