Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057725 | 0.84 | PTPN11 (0.43) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL9056650 | 0.84 | PTPN11 (0.43) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL11608197 | 0.82 | KMT2A (0.62) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL24213305 | 0.81 | NPC1 (0.59) | MEN1KMT2AL3MBTL1MAPTTDP1 | |
| SCHEMBL5838349 | 0.81 | NPC1 (0.59) | MEN1KMT2AL3MBTL1MAPTTDP1 | |
| SCHEMBL5838346 | 0.81 | NPC1 (0.59) | MEN1KMT2AL3MBTL1MAPTTDP1 | |
| SCHEMBL5184493 | 0.81 | FTO (0.56) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL11606940 | 0.81 | PTPN11 (0.48) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL29459575 | 0.81 | FTO (0.56) | MEN1POLBKMT2AL3MBTL1MAPT | |
| SCHEMBL11612113 | 0.81 | L3MBTL1 (0.56) | MEN1KMT2AL3MBTL1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131921-A1 | SILYLATED, SUBSTITUTED BENZOTRIAZOLYLPHENOL COMPOUNDS | ISDIN S.A. (ES) | 2008-11-06 | — | — | WO | disclosed |