Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK7 | P50613 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | CCNH | P51946 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057725 | 1.00 | PTPN11 (0.43) | PTPN11RAB9ANPC1CCNT1CCNB2 | |
| SCHEMBL14035302 | 0.84 | MEN1 (0.50) | PTPN11RAB9ANPC1CCNT1CCNB2 | |
| SCHEMBL9056062 | 0.77 | MAPK1 (0.53) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL24213305 | 0.77 | NPC1 (0.59) | PTPN11RAB9ANPC1CCNT1CCNB2 | |
| SCHEMBL5838349 | 0.77 | NPC1 (0.59) | PTPN11RAB9ANPC1CCNT1CCNB2 | |
| SCHEMBL5838346 | 0.77 | NPC1 (0.59) | PTPN11RAB9ANPC1CCNT1CCNB2 | |
| SCHEMBL5184493 | 0.77 | FTO (0.56) | PTPN11RAB9ANPC1PLAUMAPT | |
| SCHEMBL11612113 | 0.77 | L3MBTL1 (0.56) | PTPN11RAB9ANPC1CCNT1CCNB2 | |
| SCHEMBL29459575 | 0.77 | FTO (0.56) | PTPN11RAB9ANPC1PLAUMAPT | |
| SCHEMBL11606940 | 0.77 | PTPN11 (0.48) | PTPN11RAB9ANPC1CCNT1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012709-A1 | SUBSTITUTED BIPHENYL PYRAZINES | HOECHST CELANESE CORPORATION (US) | 1996-05-02 | — | — | WO | disclosed |
| US-5464941-A | Polymer blends for paints | HOECHST CELANESE CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| US-5464923-A | Polymer blends for paints | HOECHST CELANESE CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |