Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ESRRG | P62508 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salethamide SCHEMBL588724 | 0.90 | ALDH1A1 (0.71) | HTTHPGDALDH1A1NPC1HSD17B10 | |
| Salethamide SCHEMBL11573255 | 0.89 | ALDH1A1 (0.69) | HTTHPGDALDH1A1NPC1HSD17B10 | |
| Trencam SCHEMBL5676227 | 0.88 | ALOX5 (0.70) | HTTHPGDALDH1A1NPC1HSD17B10 | |
| SCHEMBL14868417 | 0.87 | NAAA (0.58) | HTTHPGDALDH1A1NPC1HSD17B10 | |
| SCHEMBL5707054 | 0.87 | HTT (0.69) | HTTHPGDALDH1A1NPC1HSD17B10 | |
| SCHEMBL31119120 | 0.87 | HTT (0.69) | HTTHPGDALDH1A1NPC1HSD17B10 | |
| SCHEMBL31119121 | 0.87 | HTT (0.69) | HTTHPGDALDH1A1NPC1HSD17B10 | |
| SCHEMBL8639778 | 0.86 | NAAA (0.60) | HTTHPGDALDH1A1NPC1HSD17B10 | |
| Trencam SCHEMBL5675230 | 0.86 | ALOX5 (0.68) | HTTHPGDALDH1A1NPC1HSD17B10 | |
| Trencam SCHEMBL5679535 | 0.86 | ALOX5 (0.68) | HTTHPGDALDH1A1NPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293155-A1 | SALICYLAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS | THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (US) | 2008-11-27 | — | — | US | disclosed |
| US-7404912-B2 | Salicylamide-lanthanide complexes for use as luminescent markers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-07-29 | — | — | US | disclosed |