Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982121 | 0.94 | NPC1 (0.41) | S1PR1ALDH2MAOAMAOBNR1I2 | |
| SCHEMBL14036590 | 0.94 | NPC1 (0.41) | S1PR1ALDH2MAOAMAOBNR1I2 | |
| SCHEMBL4977185 | 0.93 | L3MBTL1 (0.43) | S1PR1L3MBTL1ALDH2MAOAMAOB | |
| SCHEMBL4979511 | 0.92 | NPC1 (0.46) | L3MBTL1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL12802944 | 0.89 | PDK2 (0.44) | S1PR1MAOANR1I2PDK2ALDH1A1 | |
| SCHEMBL4978800 | 0.87 | NPC1 (0.46) | L3MBTL1ALDH2MAOAMAOBNR1I2 | |
| SCHEMBL580702 | 0.85 | MEN1 (0.47) | L3MBTL1ALDH2MAOAMAOBNPC1 | |
| SCHEMBL17993725 | 0.85 | MAPT (0.47) | MAOAMAOBPDK2MEN1KMT2A | |
| SCHEMBL4977473 | 0.85 | NPC1 (0.51) | L3MBTL1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL18012057 | 0.85 | MAPK1 (0.46) | ALDH2MAOAMAOBNR1I2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451248-B1 | 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS | CIBA HOLDING INC (CH) | 2008-11-26 | — | — | EP | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |