Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977473 | 0.94 | NPC1 (0.51) | NPC1MAPTLMNAHTTMAPK1 | |
| SCHEMBL14036384 | 0.92 | S1PR1 (0.43) | NPC1MAPTLMNAMAPK1KMT2A | |
| SCHEMBL4982121 | 0.90 | NPC1 (0.41) | NPC1MAPTLMNAMAPK1MAPK10 | |
| SCHEMBL14036590 | 0.90 | NPC1 (0.41) | NPC1MAPTLMNAMAPK1MAPK10 | |
| SCHEMBL14514279 | 0.89 | MAPT (0.49) | NPC1MAPTLMNAHTTMAPK1 | |
| SCHEMBL14036426 | 0.87 | THRB (0.39) | NPC1MAPTLMNAHTTMAPK1 | |
| SCHEMBL14514280 | 0.87 | NPC1 (0.59) | NPC1MAPTLMNAHTTMAPK1 | |
| SCHEMBL4977185 | 0.86 | L3MBTL1 (0.43) | NPC1MAPTLMNAMAPK1KMT2A | |
| SCHEMBL4980859 | 0.85 | LMNA (0.49) | NPC1MAPTLMNAHTTMAPK1 | |
| SCHEMBL3813335 | 0.85 | NPC1 (0.50) | NPC1MAPTLMNAHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451248-B1 | 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS | CIBA HOLDING INC (CH) | 2008-11-26 | — | — | EP | disclosed |
| EP-1451248-B1 | 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS | CIBA HOLDING INC (CH) | 2008-11-26 | — | — | EP | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7160949-B2 | Olefin block copolymers, processes for producing the same and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1275670-B1 | OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2005-08-10 | — | — | EP | disclosed |
| US-20050075465-A1 | 2-Hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORPORATION | 2005-04-07 | — | — | US | disclosed |
| US-20030055179-A1 | Olefin block copolymers processes for producing the same and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2003-03-20 | — | — | US | disclosed |
| EP-1275670-A1 | OLEFIN BLOCK COPOLYMERS, PRODUCTION PROCESSES OF THE SAME AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2003-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075465-A1 | 2-Hydroxyphenyl-s-triazine crosslinkers for polymer networks | H1-5, SMC4, H1-4 | NPC1 4441/4885MAPT 1803/4885LMNA 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.