Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036590 | 1.00 | NPC1 (0.41) | NPC1PDK2CA1CA2CA4 | |
| SCHEMBL14036384 | 0.94 | S1PR1 (0.43) | NPC1PDK2CA1CA2CA4 | |
| SCHEMBL12802944 | 0.94 | PDK2 (0.44) | PDK2CA1CA2CA4CA12 | |
| SCHEMBL4978800 | 0.92 | NPC1 (0.46) | NPC1PDK2CA1CA2CA4 | |
| SCHEMBL4979511 | 0.90 | NPC1 (0.46) | NPC1MAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL29389504 | 0.87 | NPC1 (0.50) | NPC1PDK2MAPTTDP1LMNA | |
| SCHEMBL29353919 | 0.87 | NPC1 (0.50) | NPC1PDK2MAPTTDP1LMNA | |
| SCHEMBL195418 | 0.87 | NPC1 (0.50) | NPC1PDK2MAPTTDP1LMNA | |
| SCHEMBL996673 | 0.87 | NPC1 (0.50) | NPC1PDK2MAPTTDP1LMNA | |
| SCHEMBL29920062 | 0.87 | NPC1 (0.50) | NPC1PDK2MAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451248-B1 | 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS | CIBA HOLDING INC (CH) | 2008-11-26 | — | — | EP | disclosed |
| EP-1451248-B1 | 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS | CIBA HOLDING INC (CH) | 2008-11-26 | — | — | EP | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |
| US-20050075465-A1 | 2-Hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORPORATION | 2005-04-07 | — | — | US | disclosed |
| EP-1451248-A1 | 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS | Ciba SC Holding AG (CH) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003046068-A1 | 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075465-A1 | 2-Hydroxyphenyl-s-triazine crosslinkers for polymer networks | H1-5, SMC4, H1-4 | NPC1 4441/4885PDK2 3593/4885CA1 2780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.