Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036426 | 0.97 | THRB (0.39) | THRBMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL4980805 | 0.92 | THRB (0.43) | THRBMAPTL3MBTL1ALDH1A1HTT | |
| SCHEMBL16191374 | 0.90 | THRB (0.44) | THRBMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL29664981 | 0.87 | THRB (0.45) | THRBMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL225454 | 0.87 | THRB (0.45) | THRBMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL16191439 | 0.86 | THRB (0.44) | THRBMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL28047260 | 0.86 | THRB (0.47) | THRBMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL2240376 | 0.85 | THRB (0.49) | THRBMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL29512611 | 0.85 | THRB (0.49) | THRBMAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL8517765 | 0.85 | THRB (0.45) | THRBMAPTPOLBGPR55LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451248-B1 | 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS | CIBA HOLDING INC (CH) | 2008-11-26 | — | — | EP | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214742-B2 | 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-05-08 | — | — | US | disclosed |