SCHEMBL8517765

SCHEMBL8517765

C=CC(=O)OCCOc1ccc(-c2nc(-c3ccc(Cl)cc3)nc(-c3ccc(OCCOC(=O)C=C)cc3O)n2)c(O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.45
KMT2A Q03164 8/20 0.42
ATM Q13315 1/20 0.42
MEN1 O00255 6/20 0.40
POLB P06746 1/20 0.39
NPSR1 Q6W5P4 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
DHFR P00374 1/20 0.36
FFAR1 O14842 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
MAPT P10636 3/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
HPGD P15428 1/20 0.35
ALOX5AP P20292 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225454 0.89 THRB (0.45) THRBKMT2AATMPOLBNPSR1
SCHEMBL29664981 0.89 THRB (0.45) THRBKMT2AATMPOLBNPSR1
SCHEMBL13897527 0.89 THRB (0.54) THRBKMT2AMEN1POLBNPSR1
SCHEMBL2240459 0.89 THRB (0.56) THRBKMT2AMEN1POLBNPSR1
SCHEMBL29512550 0.89 THRB (0.56) THRBKMT2AMEN1POLBNPSR1
SCHEMBL28047260 0.88 THRB (0.47) THRBKMT2AATMMEN1POLB
SCHEMBL4980805 0.86 THRB (0.43) THRBKMT2AMEN1NPSR1SMN1; SMN2
SCHEMBL14017595 0.86 THRB (0.51) THRBKMT2AMEN1POLBLMNA
SCHEMBL29357152 0.85 SIRT2 (0.48) KMT2AATMMEN1POLBNPSR1
SCHEMBL580703 0.85 SIRT2 (0.48) KMT2AATMMEN1POLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024074814-A9 COMPOSITION COMPRISING A FUNCTIONALISED DYE AND A DIALLYLAMINE COMONOMER AND USE THEREOF SUBLINO LIMITED (GB) 2025-05-22 WO disclosed
WO-2024074814-A1 COMPOSITION COMPRISING A FUNCTIONALISED DYE AND A DIALLYLAMINE COMONOMER AND USE SUBLINO LIMITED (GB) 2024-04-11 WO disclosed
US-5869588-A UV ABSORBERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-02-09 US disclosed
US-5672704-A ULTRAVIOLET RADIATION STABILIZERS CIBA-GEIGY CORPORATION 1997-09-30 US disclosed
EP-0706083-A1 Photographic recording material containing an UV-absorber CIBA-GEIGY AG (CH) 1996-04-10 EP disclosed