Sugi Predict

Sugi Predict / Compounds / SCHEMBL4980805

SCHEMBL4980805

SCHEMBL4980805

C=CC(=O)OCCOc1ccc(-c2nc(-c3ccc(OC)cc3)nc(-c3ccc(OCCO)cc3O)n2)c(O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 1/20 0.43
▸ MAPT P10636 10/20 0.41
▸ MAPK1 P28482 4/20 0.41
▸ KDM4E B2RXH2 3/20 0.41
▸ LMNA P02545 5/20 0.40
▸ HTT P42858 5/20 0.40
▸ NPSR1 Q6W5P4 5/20 0.40
▸ ALDH1A1 P00352 5/20 0.40
▸ TP53 P04637 2/20 0.40
▸ TSHR P16473 2/20 0.40
▸ MAPK10 P53779 2/20 0.40
▸ HPGD P15428 1/20 0.40
▸ NPC1 O15118 1/20 0.39
▸ NOD2 Q9HC29 1/20 0.39
▸ PTK2B Q14289 1/20 0.39
▸ NCOA1 Q15788 1/20 0.39
▸ NCOA3 Q9Y6Q9 1/20 0.39
▸ KMT2A Q03164 4/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ GFER P55789 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14036426 0.95 THRB (0.39) THRBMAPTMAPK1KDM4ELMNA
SCHEMBL14036387 0.92 THRB (0.41) THRBMAPTMAPK1KDM4ELMNA
SCHEMBL29664981 0.89 THRB (0.45) THRBMAPTMAPK1LMNAHTT
SCHEMBL225454 0.89 THRB (0.45) THRBMAPTMAPK1LMNAHTT
SCHEMBL28047260 0.88 THRB (0.47) THRBMAPTMAPK1LMNAHTT
SCHEMBL13897527 0.86 THRB (0.54) THRBMAPTMAPK1KDM4ELMNA
SCHEMBL8517765 0.86 THRB (0.45) THRBMAPTLMNANPSR1HPGD
SCHEMBL2240459 0.86 THRB (0.56) THRBMAPTMAPK1KDM4ELMNA
SCHEMBL29512550 0.86 THRB (0.56) THRBMAPTMAPK1KDM4ELMNA
SCHEMBL4977473 0.86 NPC1 (0.51) MAPTMAPK1KDM4ELMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1451248-B1 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS CIBA HOLDING INC (CH) 2008-11-26 — — EP disclosed
EP-1451248-B1 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS CIBA HOLDING INC (CH) 2008-11-26 — — EP disclosed
US-7214742-B2 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks CIBA SPECIALTY CHEMICALS CORP. (US) 2007-05-08 — — US disclosed
US-7214742-B2 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks CIBA SPECIALTY CHEMICALS CORP. (US) 2007-05-08 — — US disclosed
US-7214742-B2 2-hydroxyphenyl-s-triazine crosslinkers for polymer networks CIBA SPECIALTY CHEMICALS CORP. (US) 2007-05-08 — — US disclosed
US-20050075465-A1 2-Hydroxyphenyl-s-triazine crosslinkers for polymer networks CIBA SPECIALTY CHEMICALS CORPORATION 2005-04-07 — — US disclosed
EP-1451248-A1 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS Ciba SC Holding AG (CH) 2004-09-01 — — EP disclosed
WO-2003046068-A1 2-HYDROXYPHENYL-S-TRIAZINE CROSSLINKERS FOR POLYMER NETWORKS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-06-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050075465-A1 2-Hydroxyphenyl-s-triazine crosslinkers for polymer networks H1-5, SMC4, H1-4 THRB 713/4885MAPT 1803/4885MAPK1 3019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.