Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | UBE2M | P61081 | 11/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 11/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036567 | 0.89 | TACR1 (0.35) | TP53MAPTROCK2KDM4EALDH1A1 | |
| SCHEMBL14036544 | 0.88 | TP53 (0.46) | TP53MAPTUBE2MDCUN1D1 | |
| SCHEMBL14036556 | 0.88 | UBE2M (0.40) | TP53MAPTPOLBUBE2MDCUN1D1 | |
| SCHEMBL14036557 | 0.83 | NPC1 (0.47) | MAPTPOLB | |
| SCHEMBL14036548 | 0.76 | UBE2M (0.43) | TP53MAPTUBE2MDCUN1D1 | |
| SCHEMBL14036574 | 0.76 | TP53 (0.44) | TP53MAPTPOLBUBE2MDCUN1D1 | |
| SCHEMBL23585337 | 0.73 | ACHE (0.41) | POLBKDM4EUSP2ALDH1A1 | |
| SCHEMBL14036546 | 0.72 | NPC1 (0.52) | TP53MAPTHPGD | |
| SCHEMBL14036542 | 0.70 | UBE2M (0.36) | TP53MAPTUBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL14036789 | 0.68 | PTPN1 (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |