Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131811 | 0.84 | POLB (0.55) | POLBGAAGFERLMNAALDH1A1 | |
| SCHEMBL13816285 | 0.83 | GAA (0.53) | POLBGAAGFERP2RX3P2RX2 | |
| SCHEMBL4064857 | 0.83 | P2RX3 (0.55) | POLBGAAGFERP2RX3P2RX2 | |
| SCHEMBL6852792 | 0.83 | POLB (0.68) | POLBGAAGFERLMNAMEN1 | |
| SCHEMBL20373370 | 0.82 | POLB (0.45) | POLBGAAGFERLMNATSHR | |
| Thymoquinol Dimethylether SCHEMBL12613923 | 0.81 | POLB (0.66) | POLBGAAGFERLMNAMEN1 | |
| SCHEMBL14295929 | 0.81 | POLB (0.66) | POLBGAAGFERLMNAMEN1 | |
| SCHEMBL28767120 | 0.81 | LMNA (0.57) | POLBGAAGFERLMNAALDH1A1 | |
| SCHEMBL26551436 | 0.80 | POLB (0.96) | POLBGAAGFERLMNAMEN1 | |
| SCHEMBL13748156 | 0.79 | P2RX3 (0.55) | POLBGAAGFERP2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603023-A | Green synthesis method for preparing deuterated compound under illumination | 中山大学 | 2024-02-27 | — | — | CN | disclosed |
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| US-7321001-B2 | Asthma and allergic inflammation modulators | AMGEN INC. (US) | 2008-01-22 | — | — | US | disclosed |