Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19121635 | 0.84 | GAA (0.44) | POLBGAAGFERSMN1; SMN2 | |
| SCHEMBL14036622 | 0.82 | POLB (0.65) | POLBGAAGFERSMN1; SMN2TSHR | |
| SCHEMBL19984600 | 0.79 | POLB (0.45) | POLBGAAGFER | |
| SCHEMBL22796714 | 0.79 | POLB (0.41) | POLBGAAGFER | |
| SCHEMBL20794477 | 0.76 | POLB (0.38) | POLBGAAGFERLMNA | |
| SCHEMBL19308587 | 0.76 | GAA (0.47) | POLBGAAGFERTSHR | |
| SCHEMBL16736890 | 0.75 | RORC (0.46) | GAATSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL21823607 | 0.73 | LMNA (0.49) | GAASMN1; SMN2TSHRLMNA | |
| SCHEMBL31096332 | 0.73 | LMNA (0.49) | GAASMN1; SMN2TSHRLMNA | |
| SCHEMBL22838631 | 0.73 | HTR2A (0.36) | POLBGAAGFERTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345904-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.a. (IT) | 2018-07-11 | — | — | EP | disclosed |