Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036540 | 0.83 | CYP1A2 (0.41) | KCNH2PABPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14036682 | 0.78 | SLC6A4 (0.37) | KCNH2KDM4EALDH1A1SLC6A4 | |
| SCHEMBL14036776 | 0.77 | PABPC1 (0.44) | KCNH2PABPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL24619324 | 0.75 | KCNH2 (0.44) | BACE1KCNH2PABPC1CYP1A2CYP2D6 | |
| SCHEMBL29924900 | 0.75 | KCNH2 (0.44) | BACE1KCNH2PABPC1CYP1A2CYP2D6 | |
| SCHEMBL879004 | 0.73 | PABPC1 (0.42) | BACE1KCNH2PABPC1CXCR3BCHE | |
| SCHEMBL20780716 | 0.73 | DPP4 (0.43) | PABPC1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14036805 | 0.72 | MEN1 (0.40) | PABPC1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23545664 | 0.71 | ALDH1A1 (0.43) | BACE1KCNH2PABPC1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL30525076 | 0.71 | PABPC1 (0.40) | BACE1KCNH2PABPC1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |