Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036540 | 0.86 | CYP1A2 (0.41) | PABPC1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL23545664 | 0.85 | ALDH1A1 (0.43) | PABPC1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14036538 | 0.82 | KDM1A (0.57) | KDM4ETDP1MEN1KMT2AGAA | |
| SCHEMBL695073 | 0.79 | ALDH1A1 (0.49) | CYP1A2CYP2D6CYP2C9CYP2C19KDM4E | |
| SCHEMBL23545671 | 0.79 | TAAR1 (0.44) | PABPC1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL16767703 | 0.77 | KCNH2 (0.38) | PABPC1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14036626 | 0.77 | BACE1 (0.41) | PABPC1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5555894 | 0.77 | HTT (0.40) | PABPC1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5736421 | 0.76 | CYP1A2 (0.43) | PABPC1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1072948 | 0.76 | OPRL1 (0.45) | PABPC1CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |