Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4093222 | 0.70 | MAPT (0.47) | KMT2ASNCA | |
| SCHEMBL21431105 | 0.69 | PRSS1 (0.54) | ALDH1A1NPC1RAB9ALMNAMEN1 | |
| SCHEMBL14036811 | 0.69 | POLB (0.39) | POLBALDH1A1NPSR1GAAHTT | |
| SCHEMBL14036559 | 0.66 | NR4A1 (0.54) | MAPK1ALDH1A1USP2LMNAKDM4E | |
| SCHEMBL14036574 | 0.66 | TP53 (0.44) | POLBALDH1A1DDX3XUSP2KDM4E | |
| SCHEMBL14036575 | 0.66 | DDX3X (0.40) | MAPK1POLBALDH1A1NPSR1DDX3X | |
| SCHEMBL28236257 | 0.64 | ALDH1A1 (0.66) | ALDH1A1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL29739277 | 0.64 | POLB (0.69) | MAPK1POLBALDH1A1LMNAMEN1 | |
| SCHEMBL28393944 | 0.63 | POLB (0.77) | POLBALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL13099965 | 0.63 | KCNQ3 (0.49) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |