Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461162 | 0.77 | PPARG (0.36) | EPHX1PPARGCYP1A2ALDH1A1 | |
| SCHEMBL13461200 | 0.76 | GRM2 (0.39) | ALDH1A1 | |
| SCHEMBL29634236 | 0.75 | NOS1 (0.38) | EPHX1PPARGCYP1A2ALDH1A1 | |
| SCHEMBL14616077 | 0.69 | — | — | |
| SCHEMBL29634330 | 0.69 | NOS1 (0.35) | — | |
| SCHEMBL13729386 | 0.68 | — | — | |
| SCHEMBL8703630 | 0.67 | NOS1 (0.33) | EPHX1PPARGCYP1A2ALDH1A1 | |
| SCHEMBL30695179 | 0.66 | ALDH1A1 (0.39) | EPHX1PPARGCYP1A2ALDH1A1 | |
| SCHEMBL2845437 | 0.66 | CYP1A2 (0.42) | EPHX1PPARGCYP1A2ALDH1A1 | |
| SCHEMBL12993916 | 0.66 | CYP1A2 (0.42) | EPHX1PPARGCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |