SCHEMBL29634330

SCHEMBL29634330

CCCCC1C=CC=C(N)C1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 11/20 0.35
NOS2 P35228 11/20 0.35
NOS3 P29474 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29634236 0.95 NOS1 (0.38) NOS1NOS2NOS3
SCHEMBL29634235 0.89 NOS2 (0.37) NOS1NOS2NOS3
SCHEMBL23350448 0.80
SCHEMBL14616077 0.78
SCHEMBL24521825 0.72
SCHEMBL13461162 0.71 PPARG (0.36)
SCHEMBL14036797 0.69 EPHX1 (0.33)
SCHEMBL13461200 0.69 GRM2 (0.39) NOS1NOS2NOS3
SCHEMBL26340382 0.68 ALDH1A1 (0.33)
SCHEMBL18600032 0.68 NFKB1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112442022-B Benzoxazine-4-ketone compound, preparation method and medical application thereof 承德医学院 2022-05-20 CN disclosed