SCHEMBL14036889

SCHEMBL14036889

COCc1c[nH]nc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.44
ALOX15 P16050 1/20 0.41
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 6/20 0.37
MAPT P10636 2/20 0.37
GFER P55789 1/20 0.37
TDP1 Q9NUW8 4/20 0.36
SLC2A1 P11166 1/20 0.36
TTK P33981 2/20 0.35
HPGD P15428 2/20 0.35
ALPL P05186 1/20 0.35
GAA P10253 1/20 0.35
IDO1 P14902 1/20 0.35
MAPK10 P53779 1/20 0.35
LMNA P02545 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HSD17B10 Q99714 3/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025288 0.83 ALOX15 (0.38) KDM4EALOX15POLBSMN1; SMN2ALDH1A1
SCHEMBL11123121 0.81 ALOX15 (0.43) KDM4EALOX15SMN1; SMN2ALDH1A1MAPT
SCHEMBL11624564 0.79 ALOX15 (0.41) KDM4EALOX15SMN1; SMN2ALDH1A1MAPT
SCHEMBL14094653 0.79 RIPK1 (0.42) KDM4EALOX15SMN1; SMN2ALDH1A1MAPT
SCHEMBL28312868 0.78 ALOX15 (0.37) KDM4EALOX15SMN1; SMN2ALDH1A1MAPT
SCHEMBL28583866 0.78 ALOX15 (0.43) KDM4EALOX15SMN1; SMN2ALDH1A1MAPT
SCHEMBL18901018 0.78 DPP4 (0.44) KDM4EALOX15SMN1; SMN2ALDH1A1MAPT
SCHEMBL28861332 0.78 ALOX15 (0.43) KDM4EALOX15SMN1; SMN2ALDH1A1MAPT
SCHEMBL30705190 0.77 TAAR1 (0.43) KDM4EALOX15POLBALDH1A1MAPT
SCHEMBL12304043 0.77 ALOX15 (0.39) KDM4EALOX15SMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1988144-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2008-11-05 EP disclosed