Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23790876 | 0.75 | — | — | |
| SCHEMBL8994287 | 0.74 | SNCA (0.57) | SNCAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL24384601 | 0.68 | SNCA (0.39) | SNCAALDH1A1PTPN1KMT2AKDM4E | |
| SCHEMBL31095213 | 0.67 | MAPT (0.57) | SNCAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL4366398 | 0.67 | PDE3B (0.41) | SNCAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL16471403 | 0.67 | SNCA (0.53) | SNCAALDH1A1PTPN1KMT2AKDM4E | |
| SCHEMBL7346679 | 0.66 | NFKB1 (0.40) | SNCABRD4ALDH1A1KMT2AKDM4E | |
| SCHEMBL10841242 | 0.66 | ALDH1A1 (0.46) | SNCAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL9440353 | 0.64 | BRD4 (0.42) | BRD4ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL11697201 | 0.64 | HSPA1A (0.42) | SNCAALDH1A1PTPN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139287-A1 | AZETIDINE DERIVATIVES AND THEIR USE AS PROSTAGLANDIN E2 ANTAGONISTS | PFIZER LIMITED (GB) | 2008-11-20 | — | — | WO | disclosed |