SCHEMBL1403753

SCHEMBL1403753

CC(Cc1ccccc1)=C(C)C(N)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.40
PKM P14618 1/20 0.40
PTGS1 P23219 1/20 0.40
XIAP P98170 1/20 0.40
SLC7A5 Q01650 1/20 0.40
CNR2 P34972 1/20 0.40
SLC6A2 P23975 2/20 0.39
TAAR1 Q96RJ0 2/20 0.39
MAOA P21397 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
CYP2A6 P11509 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1752739 0.98 ALDH1A1 (0.40) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1403668 0.76 LMNA (0.46) ADRA2AADRA2CLMNAHIF1AKDM4E
Hydrochloric Acid SCHEMBL6369469 0.74 ALDH1A1 (0.48) ADRA2AADRA2CLMNAHIF1AKDM4E
Hydrochloric Acid SCHEMBL8593954 0.74 ALDH1A1 (0.38) SLC6A2SLC6A4SLC6A3ADRA2AADRA2C
SCHEMBL8594344 0.73 ASAH1 (0.44) CES2CES1ALDH1A1
Hydrochloric Acid SCHEMBL11054866 0.71 ASAH1 (0.43) CES2CES1ALDH1A1
Hydrochloric Acid SCHEMBL8073106 0.71 ASAH1 (0.43) CES2CES1ALDH1A1
SCHEMBL5596810 0.71 NOS2 (0.48) TAAR1CES2CES1LMNAHIF1A
SCHEMBL10528122 0.71 CES1 (0.50) CES2CES1AKR1B1ALDH1A1TSHR
SCHEMBL946139 0.71 DPP4 (0.50) CES2CES1ADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1151090-B1 MULTIPLE ENZYME ASSAYS APPLERA CORP (US) 2009-09-02 EP claimed
EP-1883635-A2 LIGHT-EMITTING BIOMARKER Quidd (FR) 2008-02-06 EP claimed
WO-2006129036-A2 LIGHT-EMITTING BIOMARKER QUIDD (FR) 2006-12-07 WO claimed
EP-1176030-B1 Ink jet recording element and printing method EASTMAN KODAK CO (US) 2005-01-12 EP claimed
US-6565953-B2 Support having thereon hydrophilic, fluid-absorbing layer, image receptive layer capable of retaining ink jet image, image-receiving layer comprising open-pore membrane of water insoluble and water-absorbent polymers; improved ink uptake EASTMAN KODAK COMPANY 2003-05-20 US claimed
US-6503607-B1 Ink jet recording element EASTMAN KODAK COMPANY 2003-01-07 US claimed
US-20030001937-A1 INK JET PRINTING METHOD EASTMAN KODAK COMPANY 2003-01-02 US claimed
US-6497481-B1 RESPONSIVE TO DIGITAL DATA SIGNALS EASTMAN KODAK COMPANY 2002-12-24 US claimed
US-6481843-B1 Ink jet printing method EASTMAN KODAK COMPANY 2002-11-19 US claimed
EP-1176030-A2 Ink jet recording element and printing method EASTMAN KODAK COMPANY (US) 2002-01-30 EP claimed
EP-2190674-B1 FUSIBLE POROUS POLYMER PARTICLES FOR INKJET RECEIVERS EASTMAN KODAK CO (US) 2011-03-09 EP disclosed
US-7858161-B2 Fusible porous polymer particles for inkjet receivers EASTMAN KODAK COMPANY (US) 2010-12-28 US disclosed
EP-2190674-A1 FUSIBLE POROUS POLYMER PARTICLES FOR INKJET RECEIVERS EASTMAN KODAK COMPANY (US) 2010-06-02 EP disclosed
EP-1321302-B1 inkjet recording element with porous organic particles EASTMAN KODAK CO (US) 2009-08-05 EP disclosed
WO-2009045277-A1 FUSIBLE POROUS POLYMER PARTICLES FOR INKJET RECEIVERS EASTMAN KODAK COMPANY (US) 2009-04-09 WO disclosed
US-6503607-B1 Ink jet recording element EASTMAN KODAK COMPANY 2003-01-07 US disclosed
US-20030001937-A1 INK JET PRINTING METHOD EASTMAN KODAK COMPANY 2003-01-02 US disclosed
US-6497481-B1 RESPONSIVE TO DIGITAL DATA SIGNALS EASTMAN KODAK COMPANY 2002-12-24 US disclosed
US-6481843-B1 Ink jet printing method EASTMAN KODAK COMPANY 2002-11-19 US disclosed
EP-1176030-A2 Ink jet recording element and printing method EASTMAN KODAK COMPANY (US) 2002-01-30 EP disclosed