SCHEMBL1403845

SCHEMBL1403845

OCCCCCCN1CCCC1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.70
MAPT P10636 3/20 0.48
CYP1A2 P05177 1/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SIGMAR1 Q99720 2/20 0.45
CXCR4 P61073 1/20 0.45
ALDH1A1 P00352 3/20 0.44
ALOX15 P16050 1/20 0.44
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1619191 1.00 HRH3 (0.70) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL1403984 1.00 HRH3 (0.70) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL3207354 1.00 HRH3 (0.70) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL1404048 1.00 HRH3 (0.70) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL30980916 1.00 HRH3 (0.70) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL1404082 1.00 HRH3 (0.70) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL1404107 0.97 HRH3 (0.75) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL11859421 0.97 HRH3 (0.75) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL1404023 0.97 HRH3 (0.75) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL9158672 0.97 HRH3 (0.75) HRH3MAPTCYP1A2MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399409-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF SE (DE) 2012-10-31 EP claimed
CN-100349851-C Method for producing acrylic acid esters BASF AG (DE) 2007-11-21 CN claimed
CN-100349854-C Method for producing (meth) acrylic acid esters BASF AG (DE) 2007-11-21 CN claimed
US-7026503-B2 Method for producing (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2006-04-11 US claimed
EP-1399408-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AG (DE) 2006-03-22 EP claimed
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
WO-2023071601-A1 DESLORATADINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 天津市昕晨投资发展有限公司 2023-05-04 WO disclosed
WO-2023071601-A1 DESLORATADINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 天津市昕晨投资发展有限公司 2023-05-04 WO disclosed
CN-115385892-A Desloratadine derivative, preparation method and application thereof 天津市昕晨投资发展有限公司 2022-11-25 CN disclosed
US-10174349-B2 Recombinant cell producing 2-hydroxyisobutyric acid EVONIK ROEHM GMBH (DE) 2019-01-08 US disclosed
EP-2291530-B1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID EVONIK ROEHM GMBH (DE) 2018-12-26 EP disclosed
CN-101186568-A Process for preparing (meth)acrylic acid EVONIK ROEHM GMBH (DE) 2008-05-28 CN disclosed
CN-101186603-A Process for preparing tetramethyl glycolide EVONIK ROEHM GMBH (DE) 2008-05-28 CN disclosed
US-20080119478-A1 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis OTSUKA PHAMACEUTICAL CO., LTD. (JP) 2008-05-22 US disclosed
EP-0382213-B1 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMA CO LTD (JP) 1995-05-10 EP disclosed
US-5053548-A Containing hydroxy substituents; nervous system disorders OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-10-01 US disclosed
EP-0382213-A2 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed
EP-0289262-A2 Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1988-11-02 EP disclosed
US-4455168-A CONTAINING A HETEROCYCLIC, HYDROXY AMINE OR AMIDE RICOH COMPANY, LTD. (JP) 1984-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119478-A1 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis NR2C2, NR0B2, NR4A2 HRH3 538/4885MAPT 4299/4885CYP1A2 420/4885
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES PLTP, LNPEP, PLIN3 HRH3 2171/4885MAPT 4029/4885CYP1A2 4878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.