Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | FOS | P01100 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14039792 | 0.88 | ANPEP (0.40) | LDHAALDH1A1SIGMAR1ALOX15ALOX12 | |
| SCHEMBL14040012 | 0.88 | LDHA (0.39) | LDHAALDH1A1SIGMAR1ALOX15ALOX12 | |
| SCHEMBL14039756 | 0.86 | LDHA (0.38) | LDHAALDH1A1SIGMAR1ALOX15ALOX12 | |
| SCHEMBL14039770 | 0.81 | ACACB (0.41) | LDHAALDH1A1KMT2AMEN1 | |
| SCHEMBL13623727 | 0.74 | SIGMAR1 (0.44) | LDHASIGMAR1ALOX15ALOX12 | |
| SCHEMBL14039804 | 0.73 | LDHA (0.40) | LDHAALDH1A1ALOX15PPARAKMT2A | |
| SCHEMBL14039920 | 0.72 | SIGMAR1 (0.40) | LDHAALDH1A1SIGMAR1ALOX15ALOX12 | |
| SCHEMBL30254854 | 0.71 | ADRA1D (0.49) | LDHASIGMAR1ALOX15ALOX12HTT | |
| SCHEMBL14040077 | 0.66 | MAPK1 (0.38) | NPC1LMNAKMT2AMEN1 | |
| SCHEMBL30254724 | 0.66 | HTR2A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697316-B1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF (R)-TAMSULOSIN AND OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THEIR PREPARATION | PROD CHIM AUXILIAIRES ET DE SY (FR) | 2008-10-08 | — | — | EP | disclosed |