Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 6/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633242 | 0.77 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL13985899 | 0.76 | ADRA1D (0.70) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL4357336 | 0.75 | ADRA1A (0.77) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL13623722 | 0.73 | ADRA1D (0.50) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL2752970 | 0.72 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL14039795 | 0.72 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL12453523 | 0.68 | ADRA1A (0.80) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL9416164 | 0.67 | ADRA1A (0.62) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| SCHEMBL14533984 | 0.66 | ADRA1A (0.79) | ADRA1DADRA1AADRA1BHTR1AADRB2 | |
| Hydrochloric Acid SCHEMBL9126140 | 0.66 | ADRA1A (0.61) | ADRA1DADRA1AADRA1BHTR1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697316-B1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF (R)-TAMSULOSIN AND OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THEIR PREPARATION | PROD CHIM AUXILIAIRES ET DE SY (FR) | 2008-10-08 | — | — | EP | disclosed |