Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 5/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13067271 | 0.86 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL10820745 | 0.86 | ADRA1D (0.69) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL4357336 | 0.83 | ADRA1A (0.77) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL13623722 | 0.82 | ADRA1D (0.50) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL14039795 | 0.81 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL14040076 | 0.77 | ADRA1D (0.44) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL9548034 | 0.75 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL51245 | 0.75 | ADRA1D (0.67) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL14040037 | 0.75 | ADRA1D (0.36) | ADRA1DADRA1AADRA1BADRB2HTR1A | |
| SCHEMBL11218388 | 0.74 | ADRA1D (0.66) | ADRA1DADRA1AADRA1BADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619116-B2 | Intermediates for the synthesis of (R)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation | Products Chimiques Auxiliaires Et de Synthese (FR) | 2009-11-17 | — | — | US | disclosed |