Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.42 |
| ▸ | VPS4B | O75351 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14040246 | 0.88 | AR (0.35) | ARVPS4BVCPKMT2AHTR1B | |
| SCHEMBL4902826 | 0.86 | AR (0.39) | ARVPS4BVCPGRIN2DGRIN3B | |
| SCHEMBL4902968 | 0.78 | SIRT1 (0.54) | ARKMT2AHTR1BSIRT1 | |
| SCHEMBL4906049 | 0.78 | SIRT1 (0.43) | ARGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20602071 | 0.78 | AR (0.42) | ARKMT2AHTR1BNR2E1MEN1 | |
| SCHEMBL4901767 | 0.75 | AR (0.39) | ARVPS4BVCPHTR1BNR2E1 | |
| SCHEMBL10746281 | 0.72 | NR2E1 (0.61) | NR2E1 | |
| SCHEMBL14041492 | 0.72 | VPS4B (0.41) | ARVPS4BVCPKMT2AHTR1B | |
| SCHEMBL14041654 | 0.71 | TAAR1 (0.50) | TRPV1NR2E1BTK | |
| SCHEMBL14040265 | 0.71 | RB1 (0.48) | VPS4BVCPGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975159-A1 | 2,3,4,9-Tetrahydro-1H-carbazoles | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-10-01 | — | — | EP | disclosed |