SCHEMBL1404040

SCHEMBL1404040

CC(C)N1CCN(CCCCO)CC1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.49
DAO P14920 1/20 0.39
SLC2A1 P11166 1/20 0.38
KDM1A O60341 1/20 0.38
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAOA P21397 3/20 0.36
MC4R P32245 1/20 0.36
PAOX Q6QHF9 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1415667 0.98 MAOB (0.50) MAOBDAOSLC2A1KDM1ATP53
SCHEMBL1404103 0.98 MAOB (0.50) MAOBDAOSLC2A1KDM1ATP53
SCHEMBL1404087 0.98 MAOB (0.50) MAOBDAOSLC2A1KDM1ATP53
SCHEMBL3201636 0.98 MAOB (0.50) MAOBDAOSLC2A1KDM1ATP53
SCHEMBL1619625 0.98 MAOB (0.50) MAOBDAOSLC2A1KDM1ATP53
SCHEMBL1619327 0.98 MAOB (0.50) MAOBDAOSLC2A1KDM1ATP53
SCHEMBL1404079 0.94 MAOB (0.46) MAOBDAOSLC2A1KDM1ATP53
SCHEMBL6656793 0.89 MAOB (0.56) MAOBDAOSLC2A1KDM1AMAOA
SCHEMBL6663625 0.87 MAOB (0.57) MAOBDAOSLC2A1KDM1AMAOA
SCHEMBL436938 0.85 ALDH1A1 (0.46) MAOBDAOKDM1AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399409-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF SE (DE) 2012-10-31 EP claimed
US-7026503-B2 Method for producing (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2006-04-11 US claimed
EP-1399408-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AG (DE) 2006-03-22 EP claimed
US-10174349-B2 Recombinant cell producing 2-hydroxyisobutyric acid EVONIK ROEHM GMBH (DE) 2019-01-08 US disclosed
EP-2291530-B1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID EVONIK ROEHM GMBH (DE) 2018-12-26 EP disclosed
CN-107083352-A Produce the recombinant cell of 2 hydroxy-iso-butyric acids 赢创罗姆有限公司 2017-08-22 CN disclosed
EP-2125771-B1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE EVONIK ROEHM GMBH (DE) 2013-03-20 EP disclosed
US-8207371-B2 Process for preparing (meth)acrylic acid EVONIK RÖHM GMBH (DE) 2012-06-26 US disclosed
US-20110171702-A1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID EVONIK ROEHM GMBH (DE) 2011-07-14 US disclosed
US-7928251-B2 Process for preparing tetramethyl glycolide EVONIK ROEHM GMBH (DE) 2011-04-19 US disclosed
EP-2291530-A1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID Evonik Röhm GmbH (DE) 2011-03-09 EP disclosed
US-20100029979-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID EVONIK ROEHM GMBH (DE) 2010-02-04 US disclosed
US-20100010276-A1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE EVONIK ROEHM GMBH (DE) 2010-01-14 US disclosed
WO-2009156214-A1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID EVONIK RÖHM GMBH (DE) 2009-12-30 WO disclosed
EP-2125771-A1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE Evonik Röhm GmbH (DE) 2009-12-02 EP disclosed
EP-2091906-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID Evonik Röhm GmbH (DE) 2009-08-26 EP disclosed
WO-2008061819-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID EVONIK RÖHM GMBH (DE) 2008-05-29 WO disclosed
WO-2008061821-A1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE EVONIK RÖHM GMBH (DE) 2008-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029979-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID MMAB, ASS1, PAM MAOB 1541/4885DAO 109/4885SLC2A1 4091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.