SCHEMBL1404046

SCHEMBL1404046

CCCCCCCCN(CC)CCCCO

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.62
ALDH1A1 P00352 2/20 0.62
HSD17B10 Q99714 1/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
TSHR P16473 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.57
KCNH2 Q12809 7/20 0.48
DNM1 Q05193 3/20 0.44
PLA2G1B P04054 1/20 0.42
PLA2G2A P14555 1/20 0.42
MGLL Q99685 1/20 0.41
KDM5A P29375 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25503186 1.00 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1403889 1.00 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL7439657 1.00 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL10513062 1.00 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL20711439 0.98 LMNA (0.59) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1403813 0.95 LMNA (0.55) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL10653971 0.95 LMNA (0.55) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL10651672 0.95 LMNA (0.55) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1403982 0.95 LMNA (0.55) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL29174048 0.95 LMNA (0.55) LMNAALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399409-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF SE (DE) 2012-10-31 EP claimed
US-7268251-B2 Method for producing (meth) acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-09-11 US claimed
US-7026503-B2 Method for producing (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2006-04-11 US claimed
EP-1399408-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AG (DE) 2006-03-22 EP claimed
US-10174349-B2 Recombinant cell producing 2-hydroxyisobutyric acid EVONIK ROEHM GMBH (DE) 2019-01-08 US disclosed
EP-2291530-B1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID EVONIK ROEHM GMBH (DE) 2018-12-26 EP disclosed
CN-107083352-A Produce the recombinant cell of 2 hydroxy-iso-butyric acids 赢创罗姆有限公司 2017-08-22 CN disclosed
EP-2125771-B1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE EVONIK ROEHM GMBH (DE) 2013-03-20 EP disclosed
US-8207371-B2 Process for preparing (meth)acrylic acid EVONIK RÖHM GMBH (DE) 2012-06-26 US disclosed
US-20110171702-A1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID EVONIK ROEHM GMBH (DE) 2011-07-14 US disclosed
US-7928251-B2 Process for preparing tetramethyl glycolide EVONIK ROEHM GMBH (DE) 2011-04-19 US disclosed
EP-2291530-A1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID Evonik Röhm GmbH (DE) 2011-03-09 EP disclosed
US-20100029979-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID EVONIK ROEHM GMBH (DE) 2010-02-04 US disclosed
US-20100010276-A1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE EVONIK ROEHM GMBH (DE) 2010-01-14 US disclosed
WO-2009156214-A1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID EVONIK RÖHM GMBH (DE) 2009-12-30 WO disclosed
EP-2125771-A1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE Evonik Röhm GmbH (DE) 2009-12-02 EP disclosed
EP-2091906-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID Evonik Röhm GmbH (DE) 2009-08-26 EP disclosed
WO-2008061819-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID EVONIK RÖHM GMBH (DE) 2008-05-29 WO disclosed
WO-2008061821-A1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE EVONIK RÖHM GMBH (DE) 2008-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029979-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID MMAB, ASS1, PAM LMNA 3634/4885ALDH1A1 181/4885HSD17B10 1400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.