SCHEMBL1404078

SCHEMBL1404078

CCCCN(CC)CCCCO

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
LMNA P02545 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TSHR P16473 1/20 0.50
KDM5A P29375 2/20 0.46
KDM4C Q9H3R0 1/20 0.46
KCNH2 Q12809 4/20 0.43
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA9 Q16790 2/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10653971 0.98 LMNA (0.55) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL10651672 0.98 LMNA (0.55) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
1,6-Hexanediol SCHEMBL8910666 0.95 LMNA (0.57) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL7439657 0.93 LMNA (0.62) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL10513062 0.93 LMNA (0.62) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL1404046 0.93 LMNA (0.62) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL25503186 0.93 LMNA (0.62) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL1403889 0.93 LMNA (0.62) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL865665 0.92 ALDH1A1 (0.50) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL465376 0.92 SMN1; SMN2 (0.45) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399409-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF SE (DE) 2012-10-31 EP claimed
CN-100349854-C Method for producing (meth) acrylic acid esters BASF AG (DE) 2007-11-21 CN claimed
CN-100349851-C Method for producing acrylic acid esters BASF AG (DE) 2007-11-21 CN claimed
US-7268251-B2 Method for producing (meth) acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-09-11 US claimed
US-7026503-B2 Method for producing (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2006-04-11 US claimed
EP-1399408-B1 METHOD FOR PRODUCING (METH)ACRYLIC ACID ESTERS BASF AG (DE) 2006-03-22 EP claimed
US-10174349-B2 Recombinant cell producing 2-hydroxyisobutyric acid EVONIK ROEHM GMBH (DE) 2019-01-08 US disclosed
EP-2291530-B1 RECOMBINANT CELL PRODUCING 2-HYDROXYISOBUTYRIC ACID EVONIK ROEHM GMBH (DE) 2018-12-26 EP disclosed
WO-2017032699-A1 METHOD FOR PRODUCING LOW-BOILING (METH)ACRYLIC ACID ESTERS BASF SE (DE) 2017-03-02 WO disclosed
CN-101186603-B Process for preparing tetramethyl glycolide EVONIK ROEHM GMBH 2014-01-08 CN disclosed
CN-101186568-B Process for preparing (meth)acrylic acid EVONIK ROEHM GMBH 2013-04-03 CN disclosed
EP-2125771-B1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE EVONIK ROEHM GMBH (DE) 2013-03-20 EP disclosed
US-8207371-B2 Process for preparing (meth)acrylic acid EVONIK RÖHM GMBH (DE) 2012-06-26 US disclosed
EP-2125771-A1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE Evonik Röhm GmbH (DE) 2009-12-02 EP disclosed
EP-2091906-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID Evonik Röhm GmbH (DE) 2009-08-26 EP disclosed
WO-2008061819-A1 PROCESS FOR PREPARING (METH)ACRYLIC ACID EVONIK RÖHM GMBH (DE) 2008-05-29 WO disclosed
WO-2008061821-A1 PROCESS FOR PREPARING TETRAMETHYL GLYCOLIDE EVONIK RÖHM GMBH (DE) 2008-05-29 WO disclosed
CN-101186603-A Process for preparing tetramethyl glycolide EVONIK ROEHM GMBH (DE) 2008-05-28 CN disclosed
CN-101186568-A Process for preparing (meth)acrylic acid EVONIK ROEHM GMBH (DE) 2008-05-28 CN disclosed
EP-0289262-A2 Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1988-11-02 EP disclosed