SCHEMBL1404100

SCHEMBL1404100

Brc1cc2sc3sccc3c2s1

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.30
TSHR P16473 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17510886 0.80 MAPT (0.32) MAPTTSHRKDM4EALDH1A1GAA
SCHEMBL6996594 0.77 KDM4E (0.32) MAPTTSHRKDM4EALDH1A1GAA
SCHEMBL19267441 0.77 HDAC3 (0.33)
SCHEMBL19220750 0.74 GPR35 (0.32)
SCHEMBL19220736 0.73
SCHEMBL137867 0.73 GPR35 (0.38) MAPTTSHRKDM4EALDH1A1GAA
SCHEMBL1997385 0.72 GPR35 (0.35)
SCHEMBL14323452 0.72 CYP1A1 (0.39) MAPTKDM4EALDH1A1GAA
SCHEMBL6999797 0.72 GPR35 (0.56) MAPTTSHRKDM4EALDH1A1GAA
SCHEMBL19267322 0.71 MAPT (0.34) MAPTTSHRKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10472373-B2 Thienothiophene/dithienothiophene-triphenylamine/tetraphenylethylene derivatives for organic light emitting diodes TUBITAK (TR) 2019-11-12 US disclosed
EP-3271364-B1 THIENOTHIOPHENE/DITHIENOTHIOPHENE - TRIPHENYLAMINE/TETRAPHENYLETHYLENE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES TUBITAK (TR) 2019-06-12 EP disclosed
US-20180093996-A1 THIENOTHIOPHENE/DITHIENOTHIOPHENE - TRIPHENYLAMINE/TETRAPHENYLETHYLENE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES TUBITAK 2018-04-05 US disclosed
EP-3271364-A1 THIENOTHIOPHENE/DITHIENOTHIOPHENE - TRIPHENYLAMINE/TETRAPHENYLETHYLENE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES Tubitak (TR) 2018-01-24 EP disclosed
WO-2016132179-A1 THIENOTHIOPHENE/DITHIENOTHIOPHENE - TRIPHENYLAMINE/TETRAPHENYLETHYLENE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES TUBITAK (TR) 2016-08-25 WO disclosed
US-9310660-B2 Organic compound and electrochromic element including the same CANON KABUSHIKI KAISHA (JP) 2016-04-12 US disclosed
EP-2291427-B1 SULFONATED POLYTHIOPHENES COMPRISING FUSED RING REPEAT UNITS SOLVAY USA INC (US) 2016-03-30 EP disclosed
US-20150153624-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2015-06-04 US disclosed
US-8906520-B2 Sulfonated polythiophenes comprising fused ring repeat units SOLVAY USA, INC. (US) 2014-12-09 US disclosed
US-20110147725-A1 SULFONATED POLYTHIOPHENES COMPRISING FUSED RING REPEAT UNITS PLEXTRONICS, INC. 2011-06-23 US disclosed
EP-2291427-A2 SULFONATED POLYTHIOPHENES COMPRISING FUSED RING REPEAT UNITS Plextronics, Inc. (US) 2011-03-09 EP disclosed
WO-2009152165-A2 SULFONATED POLYTHIOPHENES COMPRISING FUSED RING REPEAT UNITS PLEXTRONICS, INC. (US) 2009-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180093996-A1 THIENOTHIOPHENE/DITHIENOTHIOPHENE - TRIPHENYLAMINE/TETRAPHENYLETHYLENE DERIVATIVES FOR ORGANIC LIGHT EMITTING DIODES TST, OCIAD1, TPT1 MAPT 69/4885TSHR 919/4885KDM4E 2072/4885
US-20150153624-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC ELEMENT INCLUDING THE SAME ETV6, H1-0, HCN2 MAPT 3179/4885TSHR 4186/4885KDM4E 2658/4885
US-10472373-B2 Thienothiophene/dithienothiophene-triphenylamine/tetraphenylethylene derivatives for organic light emitting diodes TST, OCIAD1, TPT1 MAPT 69/4885TSHR 919/4885KDM4E 2072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.