SCHEMBL1997385

SCHEMBL1997385

Brc1cc2sc3ccsc3c2s1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.35
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1697388 0.82 GPR35 (0.39) GPR35
SCHEMBL19220750 0.81 GPR35 (0.32) GPR35
SCHEMBL407079 0.79 GPR35 (0.46) GPR35HDAC3HDAC4HDAC1HDAC7
SCHEMBL559418 0.78 GPR35 (0.37) GPR35
SCHEMBL14110041 0.78 SNCA (0.34) GPR35
SCHEMBL22993626 0.77 GPR35 (0.36) GPR35
SCHEMBL18909187 0.75 GPR35 (0.35) GPR35
SCHEMBL10045600 0.75 PKM (0.39) GPR35
SCHEMBL13801951 0.75 GPR35 (0.43) GPR35HDAC3HDAC4HDAC1HDAC7
SCHEMBL5237137 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9310660-B2 Organic compound and electrochromic element including the same CANON KABUSHIKI KAISHA (JP) 2016-04-12 US disclosed
US-9310660-B2 Organic compound and electrochromic element including the same CANON KABUSHIKI KAISHA (JP) 2016-04-12 US disclosed
EP-2291427-B1 SULFONATED POLYTHIOPHENES COMPRISING FUSED RING REPEAT UNITS SOLVAY USA INC (US) 2016-03-30 EP disclosed
US-9147848-B2 Low bandgap dicyanovinyl and tricyanovinyl oligothiophenes for solar cell applications NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2015-09-29 US disclosed
US-9147848-B2 Low bandgap dicyanovinyl and tricyanovinyl oligothiophenes for solar cell applications NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2015-09-29 US disclosed
US-9147848-B2 Low bandgap dicyanovinyl and tricyanovinyl oligothiophenes for solar cell applications NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2015-09-29 US disclosed
US-20150153624-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2015-06-04 US disclosed
US-20150153624-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2015-06-04 US disclosed
US-20150141664-A1 LOW BANDGAP DICYANOVINYL AND TRICYANOVINYL OLIGOTHIOPHENES FOR SOLAR CELL APPLICATIONS NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2015-05-21 US disclosed
US-20150141664-A1 LOW BANDGAP DICYANOVINYL AND TRICYANOVINYL OLIGOTHIOPHENES FOR SOLAR CELL APPLICATIONS NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2015-05-21 US disclosed
US-8975419-B2 Low bandgap dicyanovinyl and tricyanovinyl oligothiophenes for solar cell applications NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2015-03-10 US disclosed
US-8975419-B2 Low bandgap dicyanovinyl and tricyanovinyl oligothiophenes for solar cell applications NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) 2015-03-10 US disclosed
US-8906520-B2 Sulfonated polythiophenes comprising fused ring repeat units SOLVAY USA, INC. (US) 2014-12-09 US disclosed
US-8906520-B2 Sulfonated polythiophenes comprising fused ring repeat units SOLVAY USA, INC. (US) 2014-12-09 US disclosed
US-8906520-B2 Sulfonated polythiophenes comprising fused ring repeat units SOLVAY USA, INC. (US) 2014-12-09 US disclosed
US-20140005411-A1 LOW BANDGAP DICYANOVINYL AND TRICYANOVINYL OLIGOTHIOPHENES FOR SOLAR CELL APPLICATIONS NANO AND ADVANCED MATERIALS INSTITUTE LIMITE (HK) 2014-01-02 US disclosed
US-20110147725-A1 SULFONATED POLYTHIOPHENES COMPRISING FUSED RING REPEAT UNITS PLEXTRONICS, INC. 2011-06-23 US disclosed
US-20110147725-A1 SULFONATED POLYTHIOPHENES COMPRISING FUSED RING REPEAT UNITS PLEXTRONICS, INC. 2011-06-23 US disclosed
US-20110147725-A1 SULFONATED POLYTHIOPHENES COMPRISING FUSED RING REPEAT UNITS PLEXTRONICS, INC. 2011-06-23 US disclosed
WO-2009152165-A2 SULFONATED POLYTHIOPHENES COMPRISING FUSED RING REPEAT UNITS PLEXTRONICS, INC. (US) 2009-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141664-A1 LOW BANDGAP DICYANOVINYL AND TRICYANOVINYL OLIGOTHIOPHENES FOR SOLAR CELL APPLICATIONS DSG1, CDC73, CDC23 GPR35 1365/4885HDAC3 4121/4885HDAC4 3783/4885
US-20150153624-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC ELEMENT INCLUDING THE SAME ETV6, H1-0, HCN2 GPR35 4624/4885HDAC3 2524/4885HDAC4 2803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.