Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746837 | 0.80 | MEN1 (0.60) | ADORA3MEN1KMT2AGSTO1RAB9A | |
| SCHEMBL4746872 | 0.79 | MAPT (0.55) | ADORA3MEN1KMT2AGSTO1RAB9A | |
| SCHEMBL4747038 | 0.78 | SMN1; SMN2 (0.52) | ADORA3MEN1KMT2AGSTO1RAB9A | |
| SCHEMBL15698880 | 0.76 | CLK1 (0.58) | RAB9AKDM4ENPC1MAPTLMNA | |
| SCHEMBL12296213 | 0.74 | RAB9A (0.76) | ADORA3MEN1KMT2AGSTO1RAB9A | |
| SCHEMBL3234132 | 0.74 | HDAC3 (0.61) | MEN1KMT2ARAB9AKDM4EMAPK1 | |
| SCHEMBL20788544 | 0.74 | NPC1 (0.61) | MEN1KMT2AGSTO1RAB9AKDM4E | |
| SCHEMBL10814398 | 0.73 | MEN1 (0.83) | ADORA3MEN1KMT2AGSTO1RAB9A | |
| SCHEMBL10922779 | 0.73 | GSTO1 (0.74) | ADORA3MEN1KMT2AGSTO1RAB9A | |
| SCHEMBL12301211 | 0.73 | ADORA3 (0.76) | ADORA3MEN1KMT2AGSTO1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |