Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 18/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 16/20 | 0.52 |
| ▸ | CDK2 | P24941 | 16/20 | 0.52 |
| ▸ | CCNA1 | P78396 | 16/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13304887 | 0.86 | CHEK1 (0.44) | CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL13304791 | 0.83 | GSK3B (0.39) | CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL12953557 | 0.83 | CHEK1 (0.73) | CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL14516264 | 0.76 | CHEK1 (0.77) | CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL11931272 | 0.76 | CHEK1 (0.77) | CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL13304821 | 0.76 | GSK3B (0.53) | CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL14516261 | 0.75 | CCNA2 (0.77) | CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL14231706 | 0.74 | CHEK1 (0.78) | CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL13305036 | 0.73 | GSK3B (0.55) | CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL15026293 | 0.72 | CHEK1 (0.64) | CHEK1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130570-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |