Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | CDK2 | P24941 | 8/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14613372 | 0.87 | HDAC1 (0.41) | KDM1AHDAC1GSK3BCDK2CCNE1 | |
| SCHEMBL14581427 | 0.86 | POLB (0.47) | — | |
| SCHEMBL14545891 | 0.85 | CA12 (0.39) | KISS1RGSK3B | |
| SCHEMBL12954206 | 0.85 | ALDH1A1 (0.44) | HDAC1NAMPT | |
| SCHEMBL14418774 | 0.85 | FYN (0.41) | KISS1RGSK3B | |
| SCHEMBL14418847 | 0.85 | CSNK2A1 (0.36) | KISS1RKDM1AHDAC1IKBKBGSK3B | |
| SCHEMBL13288754 | 0.83 | CDK2 (0.45) | GSK3BCDK2CCNE1NAMPT | |
| SCHEMBL14613373 | 0.83 | EPHX2 (0.44) | HDAC1GSK3BCDK2CCNE1NAMPT | |
| SCHEMBL14613335 | 0.82 | HDAC3 (0.40) | KISS1RHDAC1GSK3BCDK2 | |
| SCHEMBL12954464 | 0.82 | GSK3B (0.39) | KISS1RGSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130570-A1 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |