SCHEMBL35727

SCHEMBL35727

COCC(C)OC(=O)C=CC#N

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.33
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NSD2 O96028 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2219863 0.85 HCAR2 (0.45) HCAR2KMT2AMEN1
SCHEMBL1404355 0.85 HCAR2 (0.45) HCAR2KMT2AMEN1
SCHEMBL1333356 0.81 HCAR2 (0.35) HCAR2MAPT
SCHEMBL26393493 0.78 HCAR2 (0.39) HCAR2
SCHEMBL8669713 0.78 HCAR2 (0.59) HCAR2ALDH1A1KDM4EMAPT
SCHEMBL8669718 0.78 HCAR2 (0.59) HCAR2ALDH1A1KDM4EMAPT
2-Octyl Cyanoacrylate SCHEMBL7867125 0.77 FAAH (0.35) ALDH1A1
SCHEMBL230497 0.77 HCAR2 (0.56) HCAR2ALDH1A1KDM4EMAPTHTT
SCHEMBL1902714 0.76 FAAH (0.40) ALDH1A1LMNA
SCHEMBL4891419 0.76 TSHR (0.35) ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4274628-A1 CATHETER SECUREMENT COMPOSITIONS AND METHODS Adhezion Biomedical, LLC (US) 2023-11-15 EP claimed
CN-117062636-A Catheter securement compositions and methods 艾德合森生物医药有限责任公司 2023-11-14 CN claimed
EP-3513744-B1 MESH DISPENSER ETHICON INC (US) 2022-11-16 EP claimed
US-11413370-B2 Adhesive-containing wound closure device and method ETHICON, INC. (US) 2022-08-16 US claimed
US-20220218951-A1 CATHETER SECUREMENT COMPOSITIONS AND METHODS PROVIDING SIGNIFICANTLY STRONG SECUREMENT, WATER RESISTANT SEAL, EFFECTIVE HEMOSTATIS, AND ANTIBACTERIAL PROPERTIES AT AND AROUND VASCULAR ACCESS SITES H.B. FULLER MEDICAL ADHESIVE TECHNOLOGIES, LLC. 2022-07-14 US claimed
WO-2022150498-A1 CATHETER SECUREMENT COMPOSITIONS AND METHODS ADHEZION BIOMEDICAL, LLC (US) 2022-07-14 WO claimed
US-20200315624-A1 Flexible Material Dispenser ETHICON INC (US) 2020-10-08 US claimed
US-10722688-B2 Device and liquid compositions for securing catheters having a rigid tapered tip ADHEZION BIOMEDICAL, LLC (US) 2020-07-28 US claimed
US-10434211-B2 Adhesive-containing wound closure device and method ETHICON, INC. (US) 2019-10-08 US claimed
EP-3513744-A1 MESH DISPENSER Ethicon, Inc. (US) 2019-07-24 EP claimed
WO-1997031598-A1 MONOMERIC COMPOSITIONS EFFECTIVE AS WOUND CLOSURE DEVICES CLOSURE MEDICAL CORPORATION (US) 1997-09-04 WO claimed
EP-0767819-A1 pH-MODIFIED BIOCOMPATIBLE MONOMER AND POLYMER COMPOSITIONS TRI-POINT MEDICAL CORPORATION (US) 1997-04-16 EP claimed
US-5582834-A APPLYING AN IN VIVO POLYMERIZABLE TISSUE ADHESIVE COMPRISING A FORMALDEHYDE SCAVENGER TRI-POINT MEDICAL, CORPORATION (US) 1996-12-10 US claimed
US-5575997-A CYANTOACRYLATES TRI-POINT MEDICAL CORPORATION (US) 1996-11-19 US claimed
EP-0727230-A2 Utilization of biocompatible adhesive/sealant materials for securing surgical devices ETHICON, INC. (US) 1996-08-21 EP claimed
US-5514371-A CYANOACRYLATES TRI-POINT MEDICAL L.P. (US) 1996-05-07 US claimed
US-5514372-A Biocompatible monomer and formaldehyde producing polymer compositions TRI-POINT MEDICAL L.P. (US) 1996-05-07 US claimed
WO-1996000760-A1 pH-MODIFIED BIOCOMPATIBLE MONOMER AND POLYMER COMPOSITIONS TRI-POINT MEDICAL CORPORATION (US) 1996-01-11 WO claimed
EP-0617973-A1 Biocompatible monomer and polymer compositions TRI-POINT MEDICAL CORPORATION (US) 1994-10-05 EP claimed
US-5328687-A Cyanoacrylate tissue adhesives, formaldehyde scavenger TRI-POINT MEDICAL L.P. (US) 1994-07-12 US claimed