SCHEMBL1404403

SCHEMBL1404403

Nc1cc(Cl)nc(C(=O)O)c1Cl.[KH]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.48
CYP3A4 P08684 1/20 0.44
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
S1PR2 O95136 1/20 0.34
SLC9A1 P19634 1/20 0.34
LMNA P02545 2/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIK1 P39086 1/20 0.33
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33
GRIA4 P48058 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIK2 Q13002 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3218994 0.98 TDP1 (0.50) TDP1CYP3A4ALDH1A1SMN1; SMN2MAPK1
SCHEMBL29390992 0.98 TDP1 (0.50) TDP1CYP3A4ALDH1A1SMN1; SMN2MAPK1
SCHEMBL116082 0.98 TDP1 (0.50) TDP1CYP3A4ALDH1A1SMN1; SMN2MAPK1
SCHEMBL28002634 0.96 TDP1 (0.48) TDP1CYP3A4ALDH1A1SMN1; SMN2MAPK1
Potassium SCHEMBL30575490 0.96 TDP1 (0.48) TDP1CYP3A4ALDH1A1SMN1; SMN2MAPK1
Dimethylamine SCHEMBL17110604 0.91 TDP1 (0.44) TDP1CYP3A4ALDH1A1SMN1; SMN2MAPK1
Butanedione SCHEMBL7585559 0.91 TDP1 (0.44) TDP1CYP3A4ALDH1A1SMN1; SMN2MAPK1
Clopyralid SCHEMBL28144775 0.88 TDP1 (0.42) TDP1CYP3A4ALDH1A1MEN1KMT2A
Pyridine SCHEMBL27930335 0.88 TDP1 (0.42) TDP1CYP3A4ALDH1A1SMN1; SMN2MAPK1
SCHEMBL20723896 0.85 TDP1 (0.40) TDP1CYP3A4ALDH1A1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12022831-B2 Synergistic weed control from applications of aminopyralid and clopyralid CORTEVA AGRISCIENCE LLC (US) 2024-07-02 US claimed
WO-2023172857-A1 THE USE OF AN AMINOPYRALID-PICLORAM-TRICLOPYR COMPOSITION TO CONTROL UNWANTED VEGETATION IN SUGARCANE CORTEVA AGRISCIENCE LLC (US) 2023-09-14 WO claimed
WO-2023172856-A1 THE USE OF AMINOPYRALID HERBICIDE COMPOSITIONS TO CONTROL WEEDS IN SUGARCANE CORTEVA AGRISCIENCE LLC (US) 2023-09-14 WO claimed
CN-115581235-A Weeding composition and application thereof 允发化工(上海)有限公司 2023-01-10 CN claimed
CN-113117559-A Compound kettle for herbicide preparation and use method thereof 安徽省圣丹生物化工有限公司 2021-07-16 CN claimed
CN-112608272-A Preparation method of picloram potassium salt bulk drug 山东埃森化学有限公司 2021-04-06 CN claimed
CN-108623516-B Method for improving color of aminopyralid 利尔化学股份有限公司 2020-08-04 CN claimed
CN-106163277-B Methods of using stable solid herbicide delivery systems 美国陶氏益农公司 2020-03-27 CN claimed
CN-106163276-B Stable solid herbicide delivery system 美国陶氏益农公司 2020-03-27 CN claimed
US-20180360028-A1 STABLE SOLID HERBICIDE DELIVERY SYSTEMS DOW AGROSCIENCES LLC 2018-12-20 US claimed
US-10098349-B2 Herbicidal compositions containing imazapic, aminopyralid and optionally metsulfuron DOW AGROSCIENCES LLC (US) 2018-10-16 US claimed
US-10015965-B2 Methods for using stable solid herbicide delivery systems DOW AGROSCIENCES LLC (US) 2018-07-10 US claimed
US-20160360750-A1 METHODS FOR USING STABLE SOLID HERBICIDE DELIVERY SYSTEMS CORTEVA AGRISCIENCE LLC 2016-12-15 US claimed
US-20160353731-A1 STABLE SOLID HERBICIDE DELIVERY SYSTEMS CORTEVA AGRISCIENCE LLC 2016-12-08 US claimed
WO-2015119513-A1 METHODS FOR USING STABLE SOLID HERBICIDE DELIVERY SYSTEMS DOW AGROSCIENCES LLC (US) 2015-08-13 WO claimed
WO-2015119514-A1 STABLE SOLID HERBICIDE DELIVERY SYSTEMS DOW AGROSCIENCES LLC (US) 2015-08-13 WO claimed
WO-2015094886-A1 HERBICIDAL COMPOSITIONS CONTAINING IMAZAPIC, AMINOPYRALID AND OPTIONALLY METSULFURON DOW AGROSCIENCES LLC (US) 2015-06-25 WO claimed
US-20150173358-A1 HERBICIDAL COMPOSITIONS CONTAINING IMAZAPIC, AMINOPYRALID AND OPTIONALLY METSULFURON DOW AGROSCIENCES LLC (US) 2015-06-25 US claimed
US-20150173364-A1 HERBICIDAL COMPOSITIONS CONTAINING FLUMIOXAZIN, AMINOPYRALID AND FLUROXYPYR OR 2,4-D DOW AGROSCIENCES LLC (US) 2015-06-25 US claimed
WO-2015094885-A1 HERBICIDAL COMPOSITIONS CONTAINING FLUMIOXAZIN, AMINOPYRALID AND FLUROXYPYR OR 2,4-D DOW AGROSCIENCES LLC (US) 2015-06-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12022831-B2 Synergistic weed control from applications of aminopyralid and clopyralid ALAD, AASDHPPT, DDT TDP1 3345/4885CYP3A4 396/4885ALDH1A1 977/4885
US-10098349-B2 Herbicidal compositions containing imazapic, aminopyralid and optionally metsulfuron DDT, ALAD, AASDHPPT TDP1 4508/4885CYP3A4 629/4885ALDH1A1 240/4885
US-20150173364-A1 HERBICIDAL COMPOSITIONS CONTAINING FLUMIOXAZIN, AMINOPYRALID AND FLUROXYPYR OR 2,4-D DDT, AASDHPPT, CYP4X1 TDP1 3248/4885CYP3A4 68/4885ALDH1A1 730/4885
US-20150173358-A1 HERBICIDAL COMPOSITIONS CONTAINING IMAZAPIC, AMINOPYRALID AND OPTIONALLY METSULFURON DDT, ALAD, AASDHPPT TDP1 4508/4885CYP3A4 629/4885ALDH1A1 240/4885
US-20160360750-A1 METHODS FOR USING STABLE SOLID HERBICIDE DELIVERY SYSTEMS DDT, GUSB, GSS TDP1 803/4885CYP3A4 458/4885ALDH1A1 1903/4885
US-20160353731-A1 STABLE SOLID HERBICIDE DELIVERY SYSTEMS SLC16A7, SLC16A3, DDT TDP1 3754/4885CYP3A4 1076/4885ALDH1A1 819/4885
US-20180360028-A1 STABLE SOLID HERBICIDE DELIVERY SYSTEMS SLC16A7, SLC16A3, DDT TDP1 3754/4885CYP3A4 1076/4885ALDH1A1 819/4885
US-10015965-B2 Methods for using stable solid herbicide delivery systems DDT, GUSB, GSS TDP1 803/4885CYP3A4 458/4885ALDH1A1 1903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.