Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13847146 | 0.82 | P2RX4 (0.39) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL13413114 | 0.81 | PIM1 (0.40) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL14044516 | 0.78 | PIM1 (0.37) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL4633656 | 0.78 | SLC1A3 (0.45) | PIM1MEN1KMT2ATDP1P2RX4 | |
| SCHEMBL8711483 | 0.76 | ALDH1A1 (0.43) | MEN1KMT2ATDP1P2RX4KDM4E | |
| SCHEMBL13529112 | 0.75 | PIM1 (0.36) | PIM1MEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL13529117 | 0.75 | SIGMAR1 (0.45) | MEN1KMT2ASIGMAR1SMPD1ALDH1A1 | |
| SCHEMBL13529109 | 0.75 | RAB9A (0.40) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29773798 | 0.70 | ALDH1A1 (0.41) | MEN1KMT2ATDP1SLC1A3SLC1A2 | |
| SCHEMBL8185089 | 0.70 | ALDH1A1 (0.41) | MEN1KMT2ATDP1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439239-B2 | Tricyclic δ- opioid modulators | JANSSEN PHARMACEUTICA N.V. (BG) | 2008-10-21 | — | — | US | disclosed |