SCHEMBL1404476

SCHEMBL1404476

O=C(O)CN(CCC(=O)OCc1ccccc1)CC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.55
CA2 P00918 8/20 0.55
ALDH1A1 P00352 3/20 0.54
MAPK1 P28482 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
CA4 P22748 2/20 0.53
TDP1 Q9NUW8 2/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KMT2A Q03164 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.44
NOTUM Q6P988 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3093075 0.89 CA1 (0.68) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL13589983 0.89 CA1 (0.68) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL20510397 0.88 CA1 (0.55) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL9162085 0.87 CA1 (0.68) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL17879692 0.86 CA1 (0.60) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL17879693 0.85 CA1 (0.66) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL17879683 0.85 CA1 (0.66) CA1CA2ALDH1A1MAPK1L3MBTL1
SCHEMBL31187902 0.84 HTT (0.52) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL23205643 0.84 ALDH1A1 (0.54) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL19862469 0.84 ALDH1A1 (0.54) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150431-A1 MHC Multimers, Methods for Their Generation, Labeling and Use DAKO DENMARK APS (DK) 2024-05-09 US disclosed
EP-3898666-A2 PANEL COMPRISING BORRELIA MHC MULTIMERS Immudex ApS (DK) 2021-10-27 EP disclosed
US-10968269-B1 MHC multimers in borrelia diagnostics and disease AGILENT TECHNOLOGIES, INC. (US) 2021-04-06 US disclosed
US-20210047383-A1 MHC Multimers in Borrelia Diagnostics and Disease DAKO DENMARK APS (DK) 2021-02-18 US disclosed
US-20200347114-A1 MHC Peptide Complexes and Uses Thereof in Infectious Diseases AGILENT TECHNOLOGIES, INC. 2020-11-05 US disclosed
US-20200347103-A1 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS AGILENT TECHNOLOGIES INC (US) 2020-11-05 US disclosed
WO-2020127222-A2 PANEL COMPRISING BORRELIA MHC MULTIMERS IMMUDEX APS (DK) 2020-06-25 WO disclosed
US-10611818-B2 MHC multimers in tuberculosis diagnostics, vaccine and therapeutics AGILENT TECHNOLOGIES, INC. (US) 2020-04-07 US disclosed
EP-3620465-A1 IMPROVED METHODS FOR GENERATION, LABELING AND USE OF MHC MULTIMERS Dako Denmark A/S (DK) 2020-03-11 EP disclosed
US-10336808-B2 MHC peptide complexes and uses thereof in infectious diseases DAKO DENMARK A/S (DK) 2019-07-02 US disclosed
WO-2010037395-A2 MHC MULTIMERS IN CANCER VACCINES AND IMMUNE MONITORING DAKO DENMARK A/S (DK) 2010-04-08 WO disclosed
WO-2010037397-A1 MHC MULTIMERS IN CMV IMMUNE MONITORING DAKO DENMARK A/S (DK) 2010-04-08 WO disclosed
EP-2167536-A1 MHC MULTIMERS, METHODS FOR THEIR GENERATION, LABELING AND USE Dako Denmark A/S (DK) 2010-03-31 EP disclosed
EP-2155782-A2 MHC PEPTIDE COMPLEXES AND USES THEREOF IN INFECTIOUS DISEASES Dako Denmark A/S (DK) 2010-02-24 EP disclosed
WO-2009106073-A2 MHC MULTIMERS IN BORRELIA DIAGNOSTICS AND DISEASE DAKO DENMARK A/S (DK) 2009-09-03 WO disclosed
WO-2009039854-A2 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS DAKO DENMARK A/S (DK) 2009-04-02 WO disclosed
WO-2009003492-A1 MHC MULTIMERS, METHODS FOR THEIR GENERATION, LABELING AND USE DAKO DENMARK A/S (DK) 2009-01-08 WO disclosed
WO-2008116468-A2 MHC PEPTIDE COMPLEXES AND USES THEREOF IN INFECTIOUS DISEASES DAKO DENMARK A/S (DK) 2008-10-02 WO disclosed
EP-1907592-A2 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES Dako Denmark A/S (DK) 2008-04-09 EP disclosed
WO-2007015168-A2 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES DAKO DENMARK A/S (US) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150431-A1 MHC Multimers, Methods for Their Generation, Labeling and Use MICA, CD74, HLA-DRB1 CA1 3018/4885CA2 4645/4885ALDH1A1 2776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.