Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886811 | 0.91 | ALOX5 (0.52) | ALDH1A1L3MBTL1MAPK1TSHRNR4A1 | |
| SCHEMBL8885275 | 0.89 | BCHE (0.52) | ALDH1A1L3MBTL1MAPK1TSHRNR4A1 | |
| SCHEMBL14439282 | 0.89 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPK1TSHRLMNA | |
| SCHEMBL14072159 | 0.86 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL19862469 | 0.84 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPK1LMNATDP1 | |
| SCHEMBL1404476 | 0.84 | CA1 (0.55) | ALDH1A1L3MBTL1MAPK1LMNATDP1 | |
| SCHEMBL19523332 | 0.83 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1TSHRNR4A1 | |
| SCHEMBL13407447 | 0.83 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1LMNATDP1 | |
| SCHEMBL25080353 | 0.83 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPK1LMNATDP1 | |
| SCHEMBL25833973 | 0.83 | BCHE (0.49) | ALDH1A1L3MBTL1MAPK1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067604-A1 | QUINOLINE INHIBITORS OF RAD52 AND METHODS OF USE | DREXEL UNIVERSITY (US) | 2021-04-08 | — | — | WO | disclosed |