SCHEMBL1404478

SCHEMBL1404478

C[C@@H](C(=O)OCc1ccccc1)N(CC(=O)O)CC(=O)O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
MAOB P27338 1/20 0.47
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
ATM Q13315 2/20 0.43
ELANE P08246 1/20 0.43
LMNA P02545 1/20 0.42
HCAR2 Q8TDS4 1/20 0.42
CTSB P07858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9841014 0.85 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3
SCHEMBL26988864 0.85 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3
SCHEMBL9841010 0.85 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3
SCHEMBL24464141 0.83 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3
SCHEMBL24514516 0.83 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3
SCHEMBL26290931 0.81 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3
SCHEMBL18510056 0.81 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3
SCHEMBL23673447 0.81 MAOB (0.45) ALDH1A1MAOBHPGDCTSB
SCHEMBL7429091 0.81 ALDH1A1 (0.60) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3
SCHEMBL10493728 0.81 ALDH1A1 (0.60) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150431-A1 MHC Multimers, Methods for Their Generation, Labeling and Use DAKO DENMARK APS (DK) 2024-05-09 US disclosed
EP-3898666-A2 PANEL COMPRISING BORRELIA MHC MULTIMERS Immudex ApS (DK) 2021-10-27 EP disclosed
US-10968269-B1 MHC multimers in borrelia diagnostics and disease AGILENT TECHNOLOGIES, INC. (US) 2021-04-06 US disclosed
US-20210047383-A1 MHC Multimers in Borrelia Diagnostics and Disease DAKO DENMARK APS (DK) 2021-02-18 US disclosed
US-20200347103-A1 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS AGILENT TECHNOLOGIES INC (US) 2020-11-05 US disclosed
US-20200347114-A1 MHC Peptide Complexes and Uses Thereof in Infectious Diseases AGILENT TECHNOLOGIES, INC. 2020-11-05 US disclosed
WO-2020127222-A2 PANEL COMPRISING BORRELIA MHC MULTIMERS IMMUDEX APS (DK) 2020-06-25 WO disclosed
US-10611818-B2 MHC multimers in tuberculosis diagnostics, vaccine and therapeutics AGILENT TECHNOLOGIES, INC. (US) 2020-04-07 US disclosed
EP-3620465-A1 IMPROVED METHODS FOR GENERATION, LABELING AND USE OF MHC MULTIMERS Dako Denmark A/S (DK) 2020-03-11 EP disclosed
US-10336808-B2 MHC peptide complexes and uses thereof in infectious diseases DAKO DENMARK A/S (DK) 2019-07-02 US disclosed
WO-2010037395-A2 MHC MULTIMERS IN CANCER VACCINES AND IMMUNE MONITORING DAKO DENMARK A/S (DK) 2010-04-08 WO disclosed
WO-2010037397-A1 MHC MULTIMERS IN CMV IMMUNE MONITORING DAKO DENMARK A/S (DK) 2010-04-08 WO disclosed
EP-2167536-A1 MHC MULTIMERS, METHODS FOR THEIR GENERATION, LABELING AND USE Dako Denmark A/S (DK) 2010-03-31 EP disclosed
EP-2155782-A2 MHC PEPTIDE COMPLEXES AND USES THEREOF IN INFECTIOUS DISEASES Dako Denmark A/S (DK) 2010-02-24 EP disclosed
WO-2009106073-A2 MHC MULTIMERS IN BORRELIA DIAGNOSTICS AND DISEASE DAKO DENMARK A/S (DK) 2009-09-03 WO disclosed
WO-2009039854-A2 MHC MULTIMERS IN TUBERCULOSIS DIAGNOSTICS, VACCINE AND THERAPEUTICS DAKO DENMARK A/S (DK) 2009-04-02 WO disclosed
WO-2009003492-A1 MHC MULTIMERS, METHODS FOR THEIR GENERATION, LABELING AND USE DAKO DENMARK A/S (DK) 2009-01-08 WO disclosed
WO-2008116468-A2 MHC PEPTIDE COMPLEXES AND USES THEREOF IN INFECTIOUS DISEASES DAKO DENMARK A/S (DK) 2008-10-02 WO disclosed
EP-1907592-A2 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES Dako Denmark A/S (DK) 2008-04-09 EP disclosed
WO-2007015168-A2 MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES DAKO DENMARK A/S (US) 2007-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150431-A1 MHC Multimers, Methods for Their Generation, Labeling and Use MICA, CD74, HLA-DRB1 ALDH1A1 2776/4885MAOB 3666/4885MAPK1 4629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.