Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841010 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL26988864 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL11165873 | 0.87 | L3MBTL1 (0.59) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL6363989 | 0.87 | L3MBTL1 (0.59) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL1404478 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KMT2AL3MBTL1LMNAMAPK1 | |
| SCHEMBL5655931 | 0.85 | KMT2A (0.56) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL12492396 | 0.85 | KMT2A (0.56) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL5655937 | 0.85 | KMT2A (0.56) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL24514516 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2AL3MBTL1LMNAMAPK1 | |
| SCHEMBL23027206 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008909-A1 | INHIBITORS OF CORONAVIRUS | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-11 | — | — | WO | disclosed |
| US-4990669-A | Optically active α-amino aldehydes, process for the preparation thereof, and the use thereof for the stereoselective preparation of optically active β-amino alcohols | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |