Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | EYA2 | O00167 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661157 | 0.90 | STING1 (0.31) | STING1 | |
| SCHEMBL6534869 | 0.88 | STING1 (0.33) | CA1STING1 | |
| SCHEMBL17177620 | 0.87 | TSHR (0.32) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL6859731 | 0.87 | TDP1 (0.47) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL2185399 | 0.87 | TDP1 (0.43) | TDP1BLMPMP22KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6840669 | 0.86 | MEN1 (0.34) | CA1STING1 | |
| SCHEMBL18362362 | 0.83 | NR1D1 (0.33) | CA1 | |
| SCHEMBL7203322 | 0.80 | TDP1 (0.38) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL18752977 | 0.79 | CA14 (0.38) | TDP1BLMPMP22KDM4ELMNA | |
| SCHEMBL2185396 | 0.79 | NR1D1 (0.35) | TDP1EYA2APPACECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10036066-B2 | In situ hybridization detection method | DAKO DENMARK A/S (DK) | 2018-07-31 | — | — | US | disclosed |
| US-9598720-B2 | Monomeric and polymeric linkers useful for conjugating biological molecules and other substances | DAKO DENMARK A/S (DK) | 2017-03-21 | — | — | US | disclosed |
| US-20160273035-A1 | IN SITU HYBRIDIZATION DETECTION METHOD | DAKO DENMARK A/S (DK) | 2016-09-22 | — | — | US | disclosed |
| EP-1919930-B1 | NEW NUCLEIC ACID BASE PAIRS | DAKO DENMARK AS (DK) | 2016-09-14 | — | — | EP | disclosed |
| US-9017992-B2 | In situ hybridization detection method | DAKO DENMARK A/S (DK) | 2015-04-28 | — | — | US | disclosed |
| EP-1910575-B1 | IMMUNOHISTOCHEMISTRY DETECTION METHOD | DAKO DENMARK AS (DK) | 2014-12-10 | — | — | EP | disclosed |
| US-8741566-B2 | Immunohistochemistry and in situ hybridization detection method | DAKO DENMARK A/S (DK) | 2014-06-03 | — | — | US | disclosed |
| US-20140080145-A1 | Monomeric and Polymeric Linkers Useful For Conjugating Biological Molecules and Other Substances | DAKO DENMARK A/S (DK) | 2014-03-20 | — | — | US | disclosed |
| US-8546309-B2 | Monomeric and polymeric linkers useful for conjugating biological molecules and other substances | DAKO DENMARK A/S (DK) | 2013-10-01 | — | — | US | disclosed |
| US-8481697-B2 | Nucleic acid base pairs | DAKO DENMARK A/S (DK) | 2013-07-09 | — | — | US | disclosed |
| US-20110177500-A1 | IMMUNOHISTOCHEMISTRY DETECTION METHOD | DAKO DENMARK AS (DK) | 2011-07-21 | — | — | US | disclosed |
| EP-1907592-B1 | MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES | DAKO DENMARK AS (DK) | 2011-03-09 | — | — | EP | disclosed |
| US-20100221705-A1 | IN SITU HYBRIDIZATION DETECTION METHOD | DAKO DENMARK APS (DK) | 2010-09-02 | — | — | US | disclosed |
| US-20100120054-A1 | MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES | DAKO DENMARK APS (DK) | 2010-05-13 | — | — | US | disclosed |
| US-20100105030-A1 | NUCLEIC ACID BASE PAIRS | DAKO DENMARK A/S (DK) | 2010-04-29 | — | — | US | disclosed |
| US-20100105145-A1 | METHOD OF SIMULTANEOUSLY VISUALIZING MULTIPLE BIOLOGICAL TARGETS | DAKO DENMARK A/S (DK) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140080145-A1 | Monomeric and Polymeric Linkers Useful For Conjugating Biological Molecules and Other Substances | PCNA, DCLRE1A, TK1 | TDP1 363/4885BLM 442/4885PMP22 1457/4885 |
| US-20100105030-A1 | NUCLEIC ACID BASE PAIRS | NSUN3, NCL, NSUN2 | TDP1 161/4885BLM 377/4885PMP22 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.