Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | YES1 | P07947 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24227347 | 0.92 | ESR1 (0.60) | ESR1ESR2CYP19A1TUBB4ATUBB | |
| SCHEMBL571732 | 0.83 | ESR2 (0.73) | ESR1ESR2CYP19A1TUBB4ATUBB | |
| SCHEMBL2029052 | 0.83 | ESR2 (0.73) | ESR1ESR2CYP19A1TUBB4ATUBB | |
| SCHEMBL15100930 | 0.83 | ESR1 (1.00) | ESR1ESR2CYP19A1TUBB4ATUBB | |
| SCHEMBL30555701 | 0.83 | ESR2 (0.73) | ESR1ESR2CYP19A1TUBB4ATUBB | |
| SCHEMBL16120884 | 0.82 | ESR1 (0.54) | ESR1ESR2CYP19A1TUBB4ATUBB | |
| SCHEMBL14045016 | 0.79 | CBS (0.55) | ESR1ESR2CYP19A1PSMB5TTR | |
| SCHEMBL4565328 | 0.77 | ESR1 (0.55) | ESR1ESR2CYP19A1TUBB4ATUBB | |
| SCHEMBL4804016 | 0.75 | ESR1 (0.58) | ESR1ESR2CYP19A1MAOBPTPN1 | |
| Garbanzol SCHEMBL29929200 | 0.74 | ESR1 (0.73) | ESR1ESR2CYP19A1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432425-B2 | Isoflavonoid methylation enzyme | THE SAMUEL ROBERTS NOBLE FOUNDATION (US) | 2008-10-07 | — | — | US | disclosed |